Results 41 to 50 of about 211,725 (313)

Fear conditioning- and extinction-induced neuronal plasticity in the mouse amygdala [PDF]

open access: yes, 2009
Experience-dependent changes in behavior are mediated by long-term functional modifications in brain circuits. To study the underlying mechanisms, our lab is using classical auditory fear conditioning, a simple and robust form of associative learning. In
Ciocchi, Stéphane
core   +1 more source

Olfactory bulb plasticity ensures proper olfaction after severe impairment in postnatal neurogenesis

open access: yesScientific Reports, 2017
The olfactory bulb (OB) neurons establish a complex network that ensures the correct processing of the olfactory inputs. Moreover, the OB presents a lifelong addition of new neurons into its existing circuitry.
D. Díaz   +5 more
doaj   +1 more source

Neuronal plasticity and antidepressant actions [PDF]

open access: yesTrends in Neurosciences, 2013
Antidepressant treatments enhance plasticity and increase neurogenesis in the adult brain, but it has been unclear how these effects influence mood. We propose that, like environmental enrichment and exercise, antidepressant treatments enhance adaptability by increasing structural variability within the nervous system at many levels, from proliferating
Eero, Castrén, René, Hen
openaire   +2 more sources

Birdsongs alleviate anxiety and paranoia in healthy participants

open access: yesScientific Reports, 2022
The present study investigated the effect of urban (traffic noise) vs. natural (birdsongs) soundscapes on mood, state paranoia, and cognitive performance, hypothesizing that birdsongs lead to significant improvements in these outcomes. An additional goal
E. Stobbe   +3 more
doaj   +1 more source

Neuronal Plasticity and Function

open access: yesClinical Neuropharmacology, 1993
Neuronal plasticity is a key issue in neuroscience. It is defined as the capability of the neuron to adapt to a changing internal or external environment, to previous experience or to trauma. It appears that during all phases of the individual life span in the nervous system, changes take place that relate to development, degeneration, and regeneration.
openaire   +3 more sources

The function of Copine 6 in the brain [PDF]

open access: yes, 2012
The formation of new or the remodeling of pre-existing synapses is thought to provide the cellular correlate of learning and memory processes. In the mammalian forebrain, the postsynaptic site of most excitatory synapses is located on dendritic spines ...
Reinhard, Judith
core   +1 more source

Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2

open access: yesFrontiers in Molecular Neuroscience, 2017
Synaptic cell adhesion molecules represent important targets for neuronal activity-dependent proteolysis. Postsynaptic neuroligins (NLs) form trans-synaptic complexes with presynaptic neurexins (NXs). Both NXs and NLs are cleaved from the cell surface by
Michelle D. Gjørlund   +9 more
doaj   +1 more source

CASK regulates CaMKII autophosphorylation in neuronal growth, calcium signalling and learning [PDF]

open access: yes, 2013
Calcium (Ca2+)/calmodulin (CaM)-dependent kinase II (CaMKII) activity plays a fundamental role in learning and memory. A key feature of CaMKII in memory formation is its ability to be regulated by autophosphorylation, which switches its activity on and ...
John M. Gillespie   +5 more
core   +1 more source

Click Chemistry (CuAAC) and Detection of Tagged de novo Synthesized Proteins in Drosophila

open access: yesBio-Protocol, 2019
Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids.
Kathrin Marter   +8 more
doaj   +1 more source

Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

open access: yesAntioxidants, 2020
Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release.
Víctor Farré-Alins   +13 more
doaj   +1 more source

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