Results 21 to 30 of about 350,715 (347)

A longitudinal, randomized experimental pilot study to investigate the effects of airborne infrasound on human mental health, cognition, and brain structure

open access: yesScientific Reports, 2021
Airborne infrasound (IS; emitted by e.g., large machinery, wind farms) is ubiquitous in technologized environments. Health hazards are controversially discussed at present.
L. Ascone   +4 more
doaj   +1 more source

Retrograde semaphorin-plexin signalling drives homeostatic synaptic plasticity. [PDF]

open access: yes, 2017
Homeostatic signalling systems ensure stable but flexible neural activity and animal behaviour. Presynaptic homeostatic plasticity is a conserved form of neuronal homeostatic signalling that is observed in organisms ranging from Drosophila to human ...
A Mahr   +37 more
core   +1 more source

The Autism Related Protein Contactin-Associated Protein-Like 2 (CNTNAP2) Stabilizes New Spines: An In Vivo Mouse Study. [PDF]

open access: yes, 2015
The establishment and maintenance of neuronal circuits depends on tight regulation of synaptic contacts. We hypothesized that CNTNAP2, a protein associated with autism, would play a key role in this process.
Gdalyahu, Amos   +5 more
core   +6 more sources

Why do mice squeak? Toward a better understanding of defensive vocalization

open access: yesiScience, 2022
Summary: Although mice mostly communicate in the ultrasonic range, they also emit audible calls. We demonstrate that mice selectively bred for high anxiety-related behavior (HAB) have a high disposition for emitting sonic calls when caught by the tail ...
Julia Ruat   +7 more
doaj   +1 more source

PTEN: A master regulator of neuronal structure, function, and plasticity. [PDF]

open access: yes, 2014
PTEN (phosphatase and tensin homolog on chromosome ten) is a dual protein/lipid phosphatase that dephosphorylates PIP3, thereby inhibiting the AKT/mTOR pathway. This inhibition ultimately decreases protein translation, cell proliferation and cell growth.
Garcia-Junco-Clemente, Pablo   +1 more
core   +1 more source

Neuronal plasticity and antidepressant actions [PDF]

open access: yesTrends in Neurosciences, 2013
Antidepressant treatments enhance plasticity and increase neurogenesis in the adult brain, but it has been unclear how these effects influence mood. We propose that, like environmental enrichment and exercise, antidepressant treatments enhance adaptability by increasing structural variability within the nervous system at many levels, from proliferating
Eero, Castrén, René, Hen
openaire   +2 more sources

Humans and dolphins: Decline and fall of adult neurogenesis [PDF]

open access: yes, 2018
Pre-clinical research is carried out on animal models, mostly laboratory rodents, with the ultimate aim of translating the acquired knowledge to humans.
Bonfanti, Luca   +2 more
core   +2 more sources

Plasticity of intrinsic neuronal excitability [PDF]

open access: yesCurrent Opinion in Neurobiology, 2019
Long-term synaptic modification is not the exclusive mode of memory storage, and persistent regulation of voltage-gated ion channels also participates in memory formation. Intrinsic plasticity is expressed in virtually all neuronal types including principal cells and interneurons.
Debanne, Dominique   +2 more
openaire   +3 more sources

STDP-driven networks and the \emph{C. elegans} neuronal network [PDF]

open access: yes, 2010
We study the dynamics of the structure of a formal neural network wherein the strengths of the synapses are governed by spike-timing-dependent plasticity (STDP). For properly chosen input signals, there exists a steady state with a residual network.
Jost, Jürgen   +3 more
core   +2 more sources

Unique potential of immature adult-born neurons for the remodeling of CA3 spatial maps

open access: yesCell Reports, 2023
Summary: Mammalian hippocampal circuits undergo extensive remodeling through adult neurogenesis. While this process has been widely studied, the specific contribution of adult-born granule cells (aGCs) to spatial operations in the hippocampus remains ...
Matías Mugnaini   +4 more
doaj   +1 more source

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