Results 11 to 20 of about 1,654,724 (346)

Autophagy in Neuronal Development and Plasticity [PDF]

open access: yesTrends in Neurosciences, 2020
Autophagy is a highly conserved intracellular clearance pathway in which cytoplasmic contents are trafficked to the lysosome for degradation. Within neurons, it helps to remove damaged organelles and misfolded or aggregated proteins and has therefore ...
David Rubinsztein, Angeleen Fleming
exaly   +5 more sources

Plasticity of intrinsic neuronal excitability. [PDF]

open access: yesCurrent Opinion in Neurobiology, 2019
Long-term synaptic modification is not the exclusive mode of memory storage, and persistent regulation of voltage-gated ion channels also participates in memory formation.
D. Debanne   +2 more
semanticscholar   +5 more sources

Cathepsins in neuronal plasticity

open access: yesNeural Regeneration Research, 2020
Proteases comprise a variety of enzymes defined by their ability to catalytically hydrolyze the peptide bonds of other proteins, resulting in protein lysis.
A. Tran, J. Silver
semanticscholar   +4 more sources

The Histone Modifications of Neuronal Plasticity [PDF]

open access: yesNeural Plasticity, 2021
Nucleosomes composed of histone octamer and DNA are the basic structural unit in the eukaryote chromosome. Under the stimulation of various factors, histones will undergo posttranslational modifications such as methylation, phosphorylation, acetylation ...
Hui-Xia Geng   +3 more
semanticscholar   +4 more sources

Oligodendrocytes and myelin limit neuronal plasticity in visual cortex. [PDF]

open access: yesNature
Developmental myelination is a protracted process in the mammalian brain1. One theory for why oligodendrocytes mature so slowly posits that myelination may stabilize neuronal circuits and temper neuronal plasticity as animals age2–4.
Xin W   +7 more
europepmc   +2 more sources

Neuronal plasticity and its role in Alzheimer's disease and Parkinson's disease. [PDF]

open access: yesNeural Regen Res
Neuronal plasticity, the brain’s ability to adapt structurally and functionally, is essential for learning, memory, and recovery from injuries. In neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease, this plasticity is ...
Jahan I   +6 more
europepmc   +2 more sources

Relation between gamma oscillations and neuronal plasticity in the visual cortex

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Learning is thought to be mediated by activity-dependent modification of neuronal interactions. To avoid maladaptive modifications of synaptic transmission by spurious activity, synaptic plasticity has to be gated.
Matthias H J Munk, Wolf Singer
exaly   +2 more sources

Keeping Neurons Young and Foxy: FoxOs Promote Neuronal Plasticity

open access: yesTrends in Genetics, 2018
Any adult who has tried to take up the piano or learn a new language is faced with the sobering realization that acquiring such skills is more challenging as an adult than as a child.
Colleen McLaughlin, Heather Broihier
exaly   +2 more sources

Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network

open access: yesNature, 2020
Behavioural experiences activate the FOS transcription factor in sparse populations of neurons that are critical for encoding and recalling specific events1–3.
Christopher Harvey   +2 more
exaly   +2 more sources

Regulation of Neuronal Differentiation, Function, and Plasticity by Alternative Splicing

open access: yesAnnual Review of Cell and Developmental Biology, 2018
Post-transcriptional mechanisms provide powerful means to expand the coding power of genomes. In nervous systems, alternative splicing has emerged as a fundamental mechanism not only for the diversification of protein isoforms but also for the spatio ...
Peter Scheiffele
exaly   +2 more sources

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