Frontiers in Molecular Neuroscience, 2017 Synaptic cell adhesion molecules represent important targets for neuronal activity-dependent proteolysis. Postsynaptic neuroligins (NLs) form trans-synaptic complexes with presynaptic neurexins (NXs). Both NXs and NLs are cleaved from the cell surface by
Michelle D. Gjørlund +9 more
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Birdsongs alleviate anxiety and paranoia in healthy participants
Scientific Reports, 2022 The present study investigated the effect of urban (traffic noise) vs. natural (birdsongs) soundscapes on mood, state paranoia, and cognitive performance, hypothesizing that birdsongs lead to significant improvements in these outcomes. An additional goal
E. Stobbe +3 more
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Rodent models of social stress and neuronal plasticity: Relevance to depressive-like disorders.
Behavioural Brain Research, 2019 Exposure to severe or persistent social stress may lead to the development of psychiatric disorders such as anxiety and depression. These mood disorders are associated with structural alterations of neural architecture in limbic brain regions that ...
D. Patel +3 more
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Neuronal Plasticity and Function
Clinical Neuropharmacology, 1993 Neuronal plasticity is a key issue in neuroscience. It is defined as the capability of the neuron to adapt to a changing internal or external environment, to previous experience or to trauma. It appears that during all phases of the individual life span in the nervous system, changes take place that relate to development, degeneration, and regeneration.
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Impairment of DHA synthesis alters the expression of neuronal plasticity markers and the brain inflammatory status in mice [PDF]
, 2020 Docosahexaenoic acid (DHA) is a ω-3 fatty acid typically obtained from the diet or endogenously synthesized through the action of elongases (ELOVLs) and desaturases.
Hessa, Tara, +23 more
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GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration
Journal of Neural Transplantation and Plasticity, 2019 In neurons, Glycogen Synthase Kinase-3β (GSK-3β) has been shown to regulate various critical processes underlying structural and functional synaptic plasticity.
Tomasz Jaworski +2 more
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Neuronal plasticity and antidepressant actions [PDF]
Trends in Neurosciences, 2013 Antidepressant treatments enhance plasticity and increase neurogenesis in the adult brain, but it has been unclear how these effects influence mood. We propose that, like environmental enrichment and exercise, antidepressant treatments enhance adaptability by increasing structural variability within the nervous system at many levels, from proliferating
Eero, Castrén, René, Hen
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Preconditioning of low-frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex [PDF]
, 2004 Recent experimental work in animals has emphasized the importance of homeostatic plasticity as a means of stabilizing the properties of neuronal circuits. Here, we report a phenomenon that indicates a homeostatic pattern of cortical plasticity in healthy
Siebner, H.R. +11 more
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Click Chemistry (CuAAC) and Detection of Tagged de novo Synthesized Proteins in Drosophila
Bio-Protocol, 2019 Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids.
Kathrin Marter +8 more
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Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux
Antioxidants, 2020 Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release.
Víctor Farré-Alins +13 more
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