Results 71 to 80 of about 1,654,724 (346)
Frontiers in Pharmacology, 2022 Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-
Irene Solés-Tarrés +11 more
doaj +1 more source
CASK regulates CaMKII autophosphorylation in neuronal growth, calcium signalling and learning [PDF]
, 2013 Calcium (Ca2+)/calmodulin (CaM)-dependent kinase II (CaMKII) activity plays a fundamental role in learning and memory. A key feature of CaMKII in memory formation is its ability to be regulated by autophosphorylation, which switches its activity on and ...
John M. Gillespie +5 more
core +1 more source
The function of Copine 6 in the brain [PDF]
, 2012 The formation of new or the remodeling of pre-existing synapses is thought to provide the cellular correlate of learning and memory processes. In the mammalian forebrain, the postsynaptic site of most excitatory synapses is located on dendritic spines ...
Reinhard, Judith
core +1 more source
Biomedicines, 2021 Traumatic brain injury (TBI) is one of the leading causes of mortality and disability worldwide without any validated biomarker or set of biomarkers to help the diagnosis and evaluation of the evolution/prognosis of TBI patients.
Víctor Farré-Alins +20 more
doaj +1 more source
Phosphorylation of the actin binding protein Drebrin at S647 and is regulated by neuronal activity and PTEN [PDF]
, 2013 Defects in actin dynamics affect activity-dependent modulation of synaptic transmission and neuronal plasticity, and can cause cognitive impairment. A salient candidate actin-binding protein linking synaptic dysfunction to cognitive deficits is Drebrin ...
Rita Hendricusdottir +31 more
core +1 more source
Social maintenance masks induced aggression in zebrafish
Scientific ReportsAnimal behavior is dynamically shaped by internal states and external social contexts. This study examines how internal states and social buffering influence aggression and social behavior.
Ashil Arroth Kuniyil +7 more
doaj +1 more source
Aggrecan Directs Extracellular Matrix-Mediated Neuronal Plasticity
Journal of Neuroscience, 2018 In the adult brain, the extracellular matrix (ECM) influences recovery after injury, susceptibility to mental disorders, and is in general a strong regulator of neuronal plasticity.
D. Rowlands +8 more
semanticscholar +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Foldscope as an Innovative Teaching Tool
Education Sciences, 2022 This study deals with the descriptive analysis of the opinion of a pilot group of students at the University of Salamanca about the use of an innovative origami microscope: the Foldscope.
Carlos Hernández-Pérez +1 more
doaj +1 more source
Neuronal plasticity and neurotrophic factors in drug responses
Molecular Psychiatry, 2017 Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other members of the neurotrophin family, are central mediators of the activity-dependent plasticity through which environmental experiences, such as sensory information are ...
E. Castrén, H. Antila
semanticscholar +1 more source