Results 31 to 40 of about 605,338 (243)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

langeec/socially-cued-plasticity: socially-cued-plasticity

open access: yes, 2020
A model of socially cued ...
Liz Lange
core   +1 more source

How feedback inhibition shapes spike-timing-dependent plasticity and its implications for recent Schizophrenia models [PDF]

open access: yes, 2011
It has been shown that plasticity is not a fixed property but, in fact, changes depending on the location of the synapse on the neuron and/or changes of biophysical parameters.
Di Prodi, P.   +18 more
core   +1 more source

Polyamine Homeostasis and Morphophysiological Responses to Salinity in Dizygostemon riparius: An Endemic Species from Brazilian ‘Cerrado’ Biome

open access: yesBiology
Dizygostemon riparius is an endemic tropical Brazilian species whose physiological responses to salinity are poorly understood. This study evaluated the effects of NaCl (0, 50, and 100 mM) on in vitro-grown D.
Jordanya Ferreira Pinheiro   +14 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A voxelwise approach to determine consensus regions-of-interest for the study of brain network plasticity

open access: yesFrontiers in Neuroanatomy, 2015
Despite exciting advances in the functional imaging of the brain, it remains a challenge to define regions of interest (ROIs) that do not require investigator supervision and permit examination of change in networks over time (or plasticity).
Sarah M. Rajtmajer   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Adaptive leaf anatomical characteristics of Brachiaria ruziziensis genotypes (Poaceae) in different environments - doi: 10.4025/actascibiolsci.v35i4.18265

open access: yesActa Scientiarum: Biological Sciences, 2013
Studies on morphological plasticity are extremely important to plant breeding seeking to optimize genotype interactions with their environments. The present study evaluated 38 genotypes of Brachiaria ruziziensis cultivated during the rainy (October to ...
Fabíola Carvalho Santos   +5 more
doaj   +1 more source

Should Root Plasticity Be a Crop Breeding Target?

open access: yesFrontiers in Plant Science, 2020
Root phenotypic plasticity has been proposed as a target for the development of more productive crops in variable environments. However, the plasticity of root anatomical and architectural responses to environmental cues is highly complex, and the ...
Hannah M. Schneider, Jonathan P. Lynch
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

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