Results 51 to 60 of about 205,434 (303)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Aberrant Origin of Splenic Artery Detected by Computed Tomography Abdominal Angiogram: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
The splenic artery is one of the terminal arteries arising from the coeliac axis, supplying the spleen, pancreas and stomach. It courses along the superior border of the pancreas and travels into the splenorenal ligament and into the hilum of the spleen,
Mohan Shobana Aparna, Sundara Raja Perumal   +1 more
doaj   +1 more source

Anatomical variations in total abdominal hysterectomy [PDF]

, 2022
2 ΕΙΣΑΓΩΓΗ – ΣΚΟΠΟΣ Με τον όρο ανατομικές παραλλαγές ορίζονται οι μη τυπικές μορφολογικές και τοπογραφικές παρουσιάσεις των ανατομικών δομών. Οι ανατομικές παραλλαγές της ελάσσονος πυέλου οι οποίες αναγνωρίζονται κατά την κοιλιακή ολική υστερεκτομή ...
Μάτσας Άλκης, Matsas Alkis
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

RARE COMBINATION OF ANATOMICAL VARIATIONS

Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular, 2020
Congenital variation of right aortic arch (prevalence 0.05%), aberrant left subclavian artery (posterior to the oesophagus) and 28*26mm diameter Kommerell diverticulum (prevalence 0.4-2.3%), with tracheal deviation and extrinsic esophageal compression.
Figueiredo Braga, Sandrina, Ferreira, Joana, Mesquita, Amílcar   +2 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Anatomical variations of the femoral vein [PDF]

Journal of Vascular Surgery, 2010
The venous anatomy is highly variable. This is due to possible venous malformations (minor truncular forms) occurring during the late development of the embryo that produce several anatomical variations in the number and caliber of the main venous femoral trunks at the thigh level.
Uhl, Jean-François, Gillot, Claude, Chahim, Maxime   +2 more
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Evaluation on the anatomic variations of the mandibular canal using cone beam computed tomography and panoramic radiography [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Some procedures in dentistry, as anesthesia, dental implants placement and third molars extraction may vary the degree of difficulty and surgical ...
Lima, Marcela Souza
core  

Development of the long head of the biceps brachial tendon: A possible explanation of the anatomical variations

, 2018
The anatomical variations of the proximal portion of the long head of the biceps brachii tendon (LHBT) are rarely observed in clinical practice. However, an increase in the rate of shoulder arthroscopic surgery has led to an increase in the observation ...
Minuesa-Asensio, Alvaro, Jorge Murillo-González, José Ramón Mérida-Velasco, Alvaro Minuesa-Asensio, Arráez Aybar, Luis Alfonso, Manuel-E. Herrera-Lara, Herrera Lara, Manuel Eugenio, Luis-A. Arráez-Aybar, Murillo González, Jorge Alfonso, Cuadra Blanco, Crótida De La, Crótida De La Cuadra-Blanco, Mérida Velasco, José Ramón   +11 more
core   +1 more source