Results 61 to 70 of about 195,307 (258)

Never undescribed before, four-headed plantaris muscle

open access: yesFolia Morphologica
The plantaris is a small muscle of the superficial posterior compartment of the leg. It originates at the lateral supracondylar line of the femur and the knee joint capsule, from where it continues distally, forming a long and slender tendon distally ...
Nicol Zielinska   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Anatomical Variations in the Formation of the Sural Nerve: A Pilot Study in a Sample of Lithuanian Cadavers

open access: yesMedicina
Background and Objectives: The sural nerve (SN) is a pure sensory nerve that supplies the lateral aspect of the ankle and foot. Its anatomical variability has been extensively documented, with multiple classifications describing its different formation ...
Artur Airapetian   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Systematic Classification of Dental Anatomical Variations and Their Impact on the Complexity of Simple Extractions

open access: yesPakistan Armed Forces Medical Journal
Objective: To categorize anatomical variations into mild, moderate, and difficult extraction scenarios, thereby providing valuable insights to new general practitioners for appropriate treatment planning before the start of the procedure to lessen post ...
Saman Malik   +5 more
doaj   +1 more source

ANATOMICAL VARIATIONS IN UPPER LIMB ARTERIES

open access: yesПаёми Сино, 2017
Upper extremity arterial disorders are less common than lower extremity disorders. Occlusion and critical stenoses of the arteries lead to the development of ischemia, during which anatomical features of the upper limbs structure play an important role ...
R.Е. КАLININ   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Sinonasal Anatomical Variations in Chronic Rhinosinusitis [PDF]

open access: yesAl-Azhar International Medical Journal
Background: Chronic rhinosinusitis (CRS) imposes a significant global health burden. The role of sinonasal anatomical variations in CRS pathogenesis remains debated, with conflicting evidence regarding their contribution to ostiomeatal complex ...
Mohamed Elsharnoby   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

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