Results 61 to 70 of about 1,860,981 (295)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Accessory spleen – a report of anatomical cases

open access: yesRussian Open Medical Journal, 2017
In the last years, there is an increase in the number of complex surgical procedures on the spleen. This process couldn’t have gone unnoticed and eventually caused a growth of interest toward this abdominal cavity organ. Acessory spleen represents one of
Natalia Mazuruc   +2 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

A cadaveric study of anatomical variations of the normal arterial pattern in hellenic population [PDF]

open access: yes, 2018
Introduction. Arterial variations may cause significant complications during diagnostic and interventional procedures. The objective of the study.
Aliki FISKA   +6 more
core   +2 more sources

RARE COMBINATION OF ANATOMICAL VARIATIONS

open access: yesRevista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular, 2020
Congenital variation of right aortic arch (prevalence 0.05%), aberrant left subclavian artery (posterior to the oesophagus) and 28*26mm diameter Kommerell diverticulum (prevalence 0.4-2.3%), with tracheal deviation and extrinsic esophageal compression.
Figueiredo Braga, Sandrina   +2 more
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Development of the long head of the biceps brachial tendon: A possible explanation of the anatomical variations

open access: yes, 2018
The anatomical variations of the proximal portion of the long head of the biceps brachii tendon (LHBT) are rarely observed in clinical practice. However, an increase in the rate of shoulder arthroscopic surgery has led to an increase in the observation ...
Minuesa-Asensio, Alvaro   +11 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

An unusual pneumatisation of turbinates

open access: yesB-ENT, 2008
An unusual pneumatisation of turbinates. Objective: To report an extremely rare case of pneumatisation of all turbinates. Case report: A 17-year-old male patient presented with nasal obstruction.
M. Sagit, C. Saka, G. Kuran, I. Akin
doaj   +2 more sources

Anatomical variations in ancient sardinian populations [PDF]

open access: yes, 2015
Archaeological excavations carried out in different burial sites of north-western Sardinia allowed to observe anatomical variations in ancient skeletal remains.
Tognotti, Eugenia   +4 more
core   +2 more sources

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