Results 81 to 90 of about 401,712 (351)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Magnetic resonance angiographic study of the anatomical variations of the anterior communicating artery complex in a turkish population [PDF]

, 2023
Hatice Kaplanoğlu, Esin Kurtuluş Öztürk   +1 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

First anatomical network analysis of fore- and hindlimb musculoskeletal modularity in bonobos, common chimpanzees, and humans [PDF]

, 2018
Studies of morphological integration and modularity, and of anatomical complexity in human evolution typically focus on skeletal tissues. Here we provide the first network analysis of the musculoskeletal anatomy of both the fore- and hindlimbs of the two
B Esteve-Altava, B Esteve-Altava, B Esteve-Altava, B Esteve-Altava, B Villmoare, C Rolian, C Rolian, C Rolian, C Rolian, D Rasskin-Gutman, EH Margulies, G Csardi, J Molnar, ME Newman, MW Marzke, MW Marzke, NM Young, NM Young, P Pons, R Diogo, R Diogo, R Diogo, R Diogo, RA Miller, S Shou, TF Hansen   +25 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Preoperative Cone Beam Computed Topography Assessment of Maxillary Sinus Variations in Dental Implant Patients

Diagnostics
This study aimed to evaluate the pathological factors and anatomical variations in the maxillary sinus in patients undergoing dental implant treatment using cone beam computed tomography (CBCT).
Alexandru Misăiloaie, Ionuț Tărăboanță, Cristian Constantin Budacu, Anca Sava   +3 more
doaj   +1 more source

Physical properties of four ring-porous hardwood species: Influence of wood rays on tangential and radial wood shrinkage [PDF]

, 2019
Some relationships between ray proportions, strength and shrinkage properties and basic density in hardwood species were highlighted. A better understanding of their relationships caused by the variation in moisture content in the hygroscopic domain ...
Candelier, Kévin, Elaieb, Mohamed Tahar, Jalleli, Mounir, Langbour, Patrick, Shel, Foued   +4 more
core   +1 more source

Anatomical variations in the digastric muscle [PDF]

The Kaohsiung Journal of Medical Sciences, 2019
The aim of this study was to investigate anatomical variations in the digastric muscle. Anatomical dissections of the head and neck region were performed in 15 cadavers at the Anatomy Department during a gross anatomy course. Three cadaver heads revealed anatomical variations in the anterior belly of the digastric muscle.
Hsiao, Tin‐Hsin, Chang, Hong‐Po
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source