Results 131 to 140 of about 736,435 (263)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metaverse-Based Virtual Reality for Remote Anatomy Education: Pilot Randomized Controlled Trial. [PDF]

open access: yesJMIR Form Res
Ha J   +17 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A STUDY ON THE BASIS OF MERIDIAN BY USE OF THE METHOD——A PRELIMIN INVESTIGATION OF THE RELATIONSHIP BETWEEN THE ACUPOINT AND VISCERA

open access: yes针刺研究, 1988
Gao Wenjun Wong Jiayin Department of Human Anatomy   +1 more
doaj  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A PRELIMINARY INVESTIGATION OF THE SEGMENTAL DISTRIBUTION OF AFFERENT FIBERS IN ACUPOINT ZILJAO (BL-32) AND UTERUS WITH HRP METHOD

open access: yes针刺研究, 1988
Gao Wenjun Weng Chiaying Department of Anatomy   +1 more
doaj  

Medical students' perceptions of radiology integration into anatomy teaching in Sudan: a cross-sectional study. [PDF]

open access: yesBMC Med Educ
Ahmed L   +6 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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