Results 141 to 150 of about 939,955 (313)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Ross and Wilson: Anatomy and physiology study guide and colouring workbook. (2nd edition) [PDF]

open access: yes, 2006
This popular workbook is based on the best-selling text Ross and Wilson: Anatomy and Physiology in Health and Illness 10/e, a favourite with an array of students including nurses, nursing students, students of the professions allied to medicine ...
Grant, Allison, Waugh, Anne
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Anatomy Department (1970) [PDF]

open access: yes
Members of the Anatomy Department. Front row: Dr Tom Dougherty, Dr Webster Jee, Dr G Taylor; Back row: Dr Walt Stevens: Dr Charles Nabors, Dr Gottlieb ...

core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Anatomy students with cadaver [PDF]

open access: yes
Four anatomy students with cadaver upon which they are resting their textbooks.8 x 8 ...
Eugene Hood, Loma Linda University Audio-Visual Services
core  

Midwifery basics. Infant feeding: anatomy and physiology [PDF]

open access: yes, 2012
Infant feeding: is the twelfth series of ‘Midwifery basics’ targeted at practising midwives, and aims to raise awareness of the impact on the work of midwives and the woman’s experience of maternity care.
Marshall, Joyce
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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