Results 201 to 210 of about 736,435 (263)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Is a 32 mm glenosphere optimal in reverse shoulder arthroplasty for patients with small glenoid anatomy? : a range of motion simulation study in petite Asian females. [PDF]

Bone Jt Open
Kiyomatsu H, Fujibuchi T, Kutsuna T, Kinoshita T, Tsuda T, Hayashi M, Shimono K, Takao M.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

CBCT-Based Epidemiological Study of Root and Root Canal Anatomy in Mandibular Second Molars in an Italian Clinical Cohort. [PDF]

J Clin Med
Greco K, Visconti RF, Paolone G, Sberna MT, Gherlone EF, Cantatore G.   +5 more
europepmc   +1 more source

Correction to “Human papillomavirus (HPV)‐18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein”

Molecular Oncology, EarlyView.
wiley   +1 more source

Correction: Assessing the Role of Ultrasound Scanning in Improving Pregnancy Outcomes in Potiskum and Neighboring Rural Communities in Yobe State, Nigeria. [PDF]

Cureus
Olagunju OJ, Egbo B, Osanyinlusi OO, Olagunju OE, Olorunmolu SE.   +4 more
europepmc   +1 more source

An Uncommon Unilateral Grade V Thumb Hypoplasia: A Cadaveric Case Report. [PDF]

Cureus
Farnum J, Cummings AL, Packard TD, Blanchard NG, McMillan W, Bradley LJ, Geske NL.   +6 more
europepmc   +1 more source

Evaluating the clinical decision-making performance of large language models in clinically oriented thoracic anatomy scenarios: a comparative evaluation study. [PDF]

BMC Med Educ
Karakoyun ZN, Yörük MD, Özdemir ME, Koşar Mİ.   +3 more
europepmc   +1 more source