Results 251 to 260 of about 1,836,350 (356)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Institutional Determinants of Academic Achievement in Biomedical Sciences: A Cross-Sectional Study of Nursing Students in Uganda. [PDF]

Adv Med Educ Pract
Munguiko C, Ngeno ACK, Atukwatse J, Museene SK.   +3 more
europepmc   +1 more source

CURE: Curriculum-guided Multi-task Training for Reliable Anatomy Grounded Report Generation [PDF]

Pablo Messina, Andrés Villa, Juan León Alcázar, Karen Sánchez, Carlos Hinojosa, Denis Parra, Álvaro Soto, Bernard Ghanemm   +7 more
openalex  

Functional Anatomy of Acrosin Inhibitors [PDF]

, 1975
Fink, Edwin, Fritz, Hans, Klauser, R., Kupfer, S., Tschesche, Harald   +4 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Radial-sheath approach for large-bore mechanical thrombectomy using the Zebra laser-cut guide catheter: Initial clinical experience. [PDF]

Interv Neuroradiol
Almasri S, Gandhi OH, Dumasia SR, Yuan S, Bagley L, Choudhri O.   +5 more
europepmc   +1 more source

Utilizing a novel highly rotatable and dual‐action sphincterotome for precise cannulation and endoscopic sphincterotomy in surgically altered anatomy [PDF]

Haruka Toyonaga, Takuya Takayama, Masaaki Shimatani   +2 more
openalex   +1 more source