Results 251 to 260 of about 2,157,998 (396)

OPTIMIZATION OF TEACHING TOPOGRAPHIC ANATOMY AND OPERATIVE SURGERY IN TERMS OF CREDIT-MODULE SYSTEM

open access: diamond, 2015
Олена Миколаївна Проніна   +3 more
openalex   +2 more sources

The Anatomy of Gallstones

open access: yesAnnals of Surgery, 1963
N A, WOMACK, R, ZEPPA, G L, IRVIN
openaire   +3 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

The anatomy of a joke

open access: yes, 2005
Juokas, kaip žodinės literatūros žanras, gali būti sėkmingai naudojamas mokant(-antis) užsienio kalbų. Humoro tyrinėtojai skiria bent du jo tipus: situacinį ir lingvistinį. Abiejų tipų humoro pagrindas yra tas pats: nevienareikšmiškumas. Situacinis humoras grindžiamas situacija, kurią galima interpretuoti daugiau nei vienu būdu.
openaire   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

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