Results 51 to 60 of about 140,572 (218)
Are We Facing the End of Gross Anatomy Teaching as We Have Known It for Centuries?
Advances in Medical Education and Practice, 2022 Ana Yoe-Cheng Chang Chan,1 Coen PM Stapper,2 Ronald LAW Bleys,3 Maarten van Leeuwen,2 Olle ten Cate4 1Department of Morphological Sciences, Faculty of Medical Sciences, National Autonomous University of Leon (UNAN-Leon), Leon, Nicaragua; 2Department of ...
Chang Chan AYC +4 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
International Medical EducationThe integration of non-immersive digital technologies into anatomy education has expanded substantially; however, their relationship with students’ academic motivation remains underexplored.
Elvira Rodriguez-Flores +8 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Student's Journal of Health Research AfricaBackground: Anatomy forms the cornerstone of medical education. While cadaveric dissection has long been the standard method for anatomy teaching, the emergence of digital platforms offering virtual dissection tools has introduced new opportunities for ...
Dr. Deepika Vazir +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Veterinary SciencesThis study evaluated the long-term effects of transitioning from traditional practical teaching to Team-Based Learning (TBL) in veterinary anatomy education.
Nieves Martín-Alguacil +4 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Enhancing Osteology Education for 1st-year Medical Students: A Peer-assisted Learning Method
Journal of the Scientific SocietyBackground: Osteology is a fundamental branch of anatomy studied by 1st-year medical students, emphasising the structure, attachments, ossification, and clinical relevance of bones. Traditional teaching methods, typically conducted as tutorials with viva-
Dhanalaxmi Neginhal +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source