Results 71 to 80 of about 92,975 (280)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Frontiers in Plant Science, 2020 Agave sensu lato is one of the most diverse and complex genera of Asparagaceae, with more than 250 species. The morphological, ecological, and evolutionary diversity of the group has complicated its taxonomical study.
Ofelia Jiménez-Barron +6 more
doaj +1 more source
A Bayesian phylogenetic hidden Markov model for B cell receptor sequence analysis. [PDF]
, 2019 The human body generates a diverse set of high affinity antibodies, the soluble form of B cell receptors (BCRs), that bind to and neutralize invading pathogens.
Dhar, Amrit +3 more
core +4 more sources
RASP 4: Ancestral State Reconstruction Tool for Multiple Genes and Characters [PDF]
Molecular Biology and Evolution, 2019 AbstractWith the continual progress of sequencing techniques, genome-scale data are increasingly used in phylogenetic studies. With more data from throughout the genome, the relationship between genes and different kinds of characters is receiving more attention.
Yan, Yu, Christopher, Blair, Xingjin, He
openaire +2 more sources
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
On the origin of Halipeurus heraldicus on Round Island petrels: cophylogenetic relationships between petrels and their chewing lice [PDF]
, 2010 Lice phylogenetic relationships have often been used to elucidate host relationships and vice versa. In this study, we investigate the louse genus Halipeurus which parasitizes bird hosts in the families Procellariidae, Hydrobatidae and Pelecanoididae ...
Brown, R. +4 more
core +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity
Angewandte Chemie, EarlyView.Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim +10 more
wiley +2 more sources
The evolution of courtship displays in Galliformes
Avian Research, 2022 Species in Galliformes have elaborate ritual courtship displays, often including strutting, fluffing of tail or head feathers, and vocal sounds that serve as excellent examples of sexual selection.
Xiyuan Guan +3 more
doaj +1 more source
Pollen morphology of Nothofagus (Nothofagaceae, Fagales) and its phylogenetic significance [PDF]
, 2016 Nothofagaceae (southern beeches) are a relatively small flowering plant family of trees confined to the Southern Hemisphere. The fossil record of the family is abundant and it has been widely used as a test case for the classic hypothesis that Antarctica,
Barreda, Viviana Dora +4 more
core +2 more sources