Results 81 to 90 of about 92,975 (280)

The Assumptions and Challenges of Ancestral State Reconstructions [PDF]

Systematic Biology, 1999
portant papers (e.g., Felsenstein, 1985; Cod? dington, 1988; Donoghue, 1989), two influ? ential books (Brooks and McLennan, 1991; Harvey and Pagel, 1991), and the computer program MacClade (Maddison and Mad? dison, 1992). But although ancestral recon?
openaire   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Neurosensory anatomy and function in Dimetrodon, the first terrestrial apex predator

iScience, 2023
Summary: Dimetrodon is among the most recognizable fossil taxa, as well as the earliest terrestrial amniote apex predator. The neuroanatomy and auditory abilities of Dimetrodon has long been the subject of interest, but palaeoneurological analyses have ...
Kayla D. Bazzana-Adams, David C. Evans, Robert R. Reisz   +2 more
doaj   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Inferring ancestral sequences in taxon-rich phylogenies [PDF]

, 2010
Statistical consistency in phylogenetics has traditionally referred to the accuracy of estimating phylogenetic parameters for a fixed number of species as we increase the number of characters. However, as sequences are often of fixed length (e.g.
Gascuel, Olivier, Steel, Mike
core  

The transcriptomic evolution of mammalian pregnancy:gene expression innovations in endometrial stromal fibroblasts [PDF]

, 2016
The endometrial stromal fibroblast (ESF) is a cell type present in the uterine lining of therian mammals. In the stem lineage of eutherian mammals, ESF acquired the ability to differentiate into decidual cells in order to allow embryo implantation.
Alyssa Birt, Arun R. Chavan, Deena Emera, Freyer, Günter P. Wagner, Hsieh-Li, Jamie Maziarz, Johnson, Koryu Kin, Laird, Manasi Kamat, Mess, Mihaela Pavlicev, Smith, Sreelakshmi Vasudevan, Troy L. Ott, Vincent J. Lynch   +16 more
core   +2 more sources

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Hidden Markov models for evolution and comparative genomics analysis. [PDF]

PLoS ONE, 2013
The problem of reconstruction of ancestral states given a phylogeny and data from extant species arises in a wide range of biological studies. The continuous-time Markov model for the discrete states evolution is generally used for the reconstruction of ...
Nadezda A Bykova, Alexander V Favorov, Andrey A Mironov   +2 more
doaj   +1 more source

From bridewealth to dowry? A Bayesian estimation of ancestral states of marriage transfers in Indo-European groups [PDF]

, 2006
Significant amounts of wealth have been exchanged as part of marriage settlements throughout history. Although various models have been proposed for interpreting these practices, their development over time has not been investigated systematically.
Fortunato, L, Holden, C, Mace, R
core