Results 91 to 100 of about 93,688 (317)

Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska

open access: yesACR Open Rheumatology
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Vivek R. Mehta   +5 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Juvenile Problems and the Law: Teacher's Manual [PDF]

open access: yes, 1976
See "Law Related Education Project: Final Report" (1976) for a description of the project under which this teacher's manual was developed. All four supplementary teacher's manuals developed under this project are also available in Scholarworks@UA ...
Anchorage School District   +1 more
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

COVID-19 Panel Survey in the Municipality of Anchorage: Highlights [PDF]

open access: yes, 2020
A panel survey of 316 individuals was conducted from May 20 to May 22, which was a follow-up to the phone survey conducted two weeks prior. Based on the results of the panel survey, the overall risk of infection by COVID-19 significantly increased in ...
Hennessy, Thomas   +8 more
core  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

The Strength of Association: Housing Density and Delinquency [PDF]

open access: yes, 2004
This issue is the first of three in Series 3a, "The Strength of Community-level Rates of Association," mapping Anchorage neighborhood characteristics by census block area, highlighting the correlation or lack of correlation between those characteristics ...
Justice Center, University of Alaska Anchorage
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

CALCULATION ASSESSMENT OF ANCHORAGE IN CONCRETE FOR FIBERGLASS REINFORCEMENT MANUFACTURED IN THE REPUBLIC OF BELARUS

open access: yesНаука и техника, 2016
The paper analyzes advantages and disadvantages of composite reinforcement while reinforcing concrete structures. Results of experimental investigations on adhesion strength of fiberglass reinforcement manufactured in the Republic of Belarus with ...
E. Ya. Sadin
doaj   +1 more source

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