Results 71 to 80 of about 109,148 (314)

Bias Estimation and Downscaling for Regional Climate Models Using Gaussian Process Regression

IEEE Access
General circulation models are widely used to predict changes in regional climate under various pathways of projected carbon emissions. These global models are spatially coarse and are commonly downscaled to provide useful predictions at regional scales.
Matthew Kupilik, Frank Witmer, Olivia Grill   +2 more
doaj   +1 more source

An Examination of Police Service Deployment: Serious Property Crime [PDF]

, 2004
This issue of Anchorage Community Indicators maps the rates by census block area and community council of Anchorage Police Department calls for service in 2003 for serious property crime in ...
Justice Center, University of Alaska Anchorage
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Effect of tree-ring detrending method on apparent growth trends of black and white spruce in interior Alaska

Environmental Research Letters, 2016
Boreal forests are critical sinks in the global carbon cycle. However, recent studies have revealed increasing frequency and extent of wildfires, decreasing landscape greenness, increasing tree mortality and declining growth of black and white spruce in ...
Patrick F Sullivan, Robert R Pattison, Annalis H Brownlee, Sean M P Cahoon, Teresa N Hollingsworth   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SEASONAL VARIATION OF NUTRITIONAL HORMONES IN CAPTIVE FEMALE MOOSE

Alces, 2017
The health status of animals may be inferred from the patterns of hormonal concentrations and other chemical characteristics in blood samples. Baseline endocrine data representing the nutritional and reproductive condition of moose are currently unknown.
Cory J. Stantorf, C. Loren Buck, Duane H. Keisler, William B. Collins, Donald E. Spalinger   +4 more
doaj  

An Examination of Police Service Deployment: Domestic Violence [PDF]

, 2004
This issue of Anchorage Community Indicators maps the rates by census block area and community council of Anchorage Police Department calls for service in 2003 for domestic violence in ...
Justice Center, University of Alaska Anchorage
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

An Examination of Police Service Deployment: Weapons Offenses [PDF]

, 2004
This issue of Anchorage Community Indicators maps the rates by census block area and community council of Anchorage Police Department calls for service in 2003 for weapons offenses in ...
Justice Center, University of Alaska Anchorage
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source