Results 61 to 70 of about 93,688 (317)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Implants for orthodontic anchorage
Implantanchorage continues to receive much attention as an important orthodontic anchorage. Since the development of orthodontic implants, the scope of applications has continued to increase. Although multiple reviews detailing implants have been published, no comprehensive evaluations have been performed.
Zheng, Xiaowen +5 more
openaire +2 more sources
Courts and Trials: Teacher's Manual [PDF]
See "Law Related Education Project: Final Report" (1976) for a description of the project under which this teacher's manual was developed. All four supplementary teacher's manuals developed under this project are also available in Scholarworks@UA ...
Anchorage School District +1 more
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
An Examination of Police Service Deployment: Alcohol Offenses [PDF]
This issue of Anchorage Community Indicators maps the rates by census block area and community council of Anchorage Police Department calls for service in 2003 for alcohol offenses in ...
Justice Center, University of Alaska Anchorage
core
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Boreal forests are critical sinks in the global carbon cycle. However, recent studies have revealed increasing frequency and extent of wildfires, decreasing landscape greenness, increasing tree mortality and declining growth of black and white spruce in ...
Patrick F Sullivan +4 more
doaj +1 more source
Relationship of bone and soft tissue thickness with age and gender for orthodontic mini-implant placement by CBCT [PDF]
Background and aim: The aim of the present study was to measure the thicknesses of bone and soft issues in the mid palatal area at certain points for the placement of orthodontic mini-implants using CBCT and evaluate their relationships with age and ...
Masoumeh Johari +3 more
doaj +1 more source
Lawmaking: Teacher's Manual [PDF]
See "Law Related Education Project: Final Report" (1976) for a description of the project under which this teacher's manual was developed. All four supplementary teacher's manuals developed under this project are also available in Scholarworks@UA ...
Anchorage School District +1 more
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source

