Results 61 to 70 of about 109,148 (314)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Density of Police Calls-for-Service, 2003: Drug-Related Incidents [PDF]

open access: yes, 2004
This issue of Anchorage Community Indicators maps the density of Anchorage Police Department calls for service in 2003 for drug-related incidents in ...
Justice Center, University of Alaska Anchorage
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A Noble, Easy and Conceptual Radiographic Analysis to Assess the Type of Tooth Movement (Molar Distalization) [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Context and Aim: Bodily tooth movement is desirable in the field of Orthodontics and so is with molar distalization. Till date there is no such analysis available which could gauge and quantify the molar distalization and the type of tooth movement ...
Abhishek Bansal   +3 more
doaj   +1 more source

Density of Police Calls-for-Service, 2003: Weapons Offenses [PDF]

open access: yes, 2004
This issue of Anchorage Community Indicators maps the density of Anchorage Police Department calls for service in 2003 for serious weapons offense in ...
Justice Center, University of Alaska Anchorage
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

White spruce presence increases leaf miner effects on aspen growth in interior Alaska

open access: yesFrontiers in Forests and Global Change
Alaska’s boreal forests are experiencing rapid changes in climate that may favor deciduous-dominated systems, with important implications for global biogeochemical and energy cycles. However, aspen (Populus tremuloides Michx.) has experienced substantial
Sean M. P. Cahoon   +4 more
doaj   +1 more source

Implants for orthodontic anchorage

open access: yesMedicine, 2018
Implantanchorage continues to receive much attention as an important orthodontic anchorage. Since the development of orthodontic implants, the scope of applications has continued to increase. Although multiple reviews detailing implants have been published, no comprehensive evaluations have been performed.
Zheng, Xiaowen   +5 more
openaire   +2 more sources

An Examination of Police Service Deployment: Alcohol Offenses [PDF]

open access: yes, 2004
This issue of Anchorage Community Indicators maps the rates by census block area and community council of Anchorage Police Department calls for service in 2003 for alcohol offenses in ...
Justice Center, University of Alaska Anchorage
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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