Results 61 to 70 of about 93,688 (317)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Implants for orthodontic anchorage

open access: yesMedicine, 2018
Implantanchorage continues to receive much attention as an important orthodontic anchorage. Since the development of orthodontic implants, the scope of applications has continued to increase. Although multiple reviews detailing implants have been published, no comprehensive evaluations have been performed.
Zheng, Xiaowen   +5 more
openaire   +2 more sources

Courts and Trials: Teacher's Manual [PDF]

open access: yes, 1976
See "Law Related Education Project: Final Report" (1976) for a description of the project under which this teacher's manual was developed. All four supplementary teacher's manuals developed under this project are also available in Scholarworks@UA ...
Anchorage School District   +1 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

An Examination of Police Service Deployment: Alcohol Offenses [PDF]

open access: yes, 2004
This issue of Anchorage Community Indicators maps the rates by census block area and community council of Anchorage Police Department calls for service in 2003 for alcohol offenses in ...
Justice Center, University of Alaska Anchorage
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Effect of tree-ring detrending method on apparent growth trends of black and white spruce in interior Alaska

open access: yesEnvironmental Research Letters, 2016
Boreal forests are critical sinks in the global carbon cycle. However, recent studies have revealed increasing frequency and extent of wildfires, decreasing landscape greenness, increasing tree mortality and declining growth of black and white spruce in ...
Patrick F Sullivan   +4 more
doaj   +1 more source

Relationship of bone and soft tissue thickness with age and gender for orthodontic mini-implant placement by CBCT [PDF]

open access: yesIranian Journal of Orthodontics, 2012
Background and aim: The aim of the present study was to measure the thicknesses of bone and soft issues in the mid palatal area at certain points for the placement of orthodontic mini-implants using CBCT and evaluate their relationships with age and ...
M‪asoumeh Johari   +3 more
doaj   +1 more source

Lawmaking: Teacher's Manual [PDF]

open access: yes, 1976
See "Law Related Education Project: Final Report" (1976) for a description of the project under which this teacher's manual was developed. All four supplementary teacher's manuals developed under this project are also available in Scholarworks@UA ...
Anchorage School District   +1 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy