Results 51 to 60 of about 65,950 (266)

Effect of tree-ring detrending method on apparent growth trends of black and white spruce in interior Alaska

Environmental Research Letters, 2016
Boreal forests are critical sinks in the global carbon cycle. However, recent studies have revealed increasing frequency and extent of wildfires, decreasing landscape greenness, increasing tree mortality and declining growth of black and white spruce in ...
Patrick F Sullivan, Robert R Pattison, Annalis H Brownlee, Sean M P Cahoon, Teresa N Hollingsworth   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Implants for orthodontic anchorage

Medicine, 2018
Implantanchorage continues to receive much attention as an important orthodontic anchorage. Since the development of orthodontic implants, the scope of applications has continued to increase. Although multiple reviews detailing implants have been published, no comprehensive evaluations have been performed.
Zheng, Xiaowen, Sun, Yannan, Zhang, Yimei, Cai, Ting, Sun, Feng, Lin, Jiuxiang   +5 more
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

White spruce presence increases leaf miner effects on aspen growth in interior Alaska

Frontiers in Forests and Global Change
Alaska’s boreal forests are experiencing rapid changes in climate that may favor deciduous-dominated systems, with important implications for global biogeochemical and energy cycles. However, aspen (Populus tremuloides Michx.) has experienced substantial
Sean M. P. Cahoon, Colin Maher, Colin Maher, Daniel Crawford, Patrick F. Sullivan   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Bias Estimation and Downscaling for Regional Climate Models Using Gaussian Process Regression

IEEE Access
General circulation models are widely used to predict changes in regional climate under various pathways of projected carbon emissions. These global models are spatially coarse and are commonly downscaled to provide useful predictions at regional scales.
Matthew Kupilik, Frank Witmer, Olivia Grill   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

SEASONAL VARIATION OF NUTRITIONAL HORMONES IN CAPTIVE FEMALE MOOSE

Alces, 2017
The health status of animals may be inferred from the patterns of hormonal concentrations and other chemical characteristics in blood samples. Baseline endocrine data representing the nutritional and reproductive condition of moose are currently unknown.
Cory J. Stantorf, C. Loren Buck, Duane H. Keisler, William B. Collins, Donald E. Spalinger   +4 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source