Results 41 to 50 of about 2,524,307 (296)

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

Disentangling the cultural evolution of ancient China: a digital humanities perspective

open access: yesHumanities & Social Sciences Communications, 2023
Being recognized among the cradles of human civilization, ancient China nurtured the longest continuous academic traditions and humanistic spirits, which continue to impact today’s society.
Siyu Duan, Jun Wang, Hao Yang, Qi Su
doaj   +1 more source

CaMKIIδ Phosphorylates AUP1 to Promote Pancreatic Tissue Repair and Acinar‐to‐Ductal Metaplasia Formation via Mediating PERK‐Dependent Unfolded Protein Responses

open access: yesAdvanced Science, EarlyView.
CaMKIIδ–AUP1 signaling maintains PERK‐dependent ER homeostasis during ADM‐mediated pancreatic repair. ABSTRACT Pancreatic repair after acute pancreatitis (AP) is essential for restoring tissue integrity, but the intrinsic mechanisms coordinating acinar plasticity and regeneration remain poorly understood.
Yonghao Chen   +10 more
wiley   +1 more source

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

open access: yesAdvanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao   +13 more
wiley   +1 more source

Continuity and innovation in imperial inscriptions. Augustus’ Res Gestae and the Stelae of the Qin First Emperor Compared

open access: yesNew Classicists, 2020
In the east under the Qin First Emperor and in the west under Augustus, who both established new regimes after a period of internal wars and expanded their territories enormously, an idea of universal ‘empire’ (orbis terrarum and ‘All-under-Heaven ...
Chen Xiong
doaj  

FengShui – a systematic research of vernacular sustainable development In Ancient China and its lessons for future [PDF]

open access: yes, 2007
Creating and keeping balance is the basic and the most important principle of Chinese traditional\ud philosophy. It provides the fundamental philosophical basis for Chinese FengShui in pursuing\ud coexistence between human and nature.
Zhong, Z., Ceranic, Boris
core  

Hydration Behavior of Tricalcium Silicate in Seawater Relevant Salt Systems: A Hybrid Study with the Aid of Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
The hydration behavior of C3S in seawater‐relevant solutions is studied based on experiments, boundary nucleation and growth (BNG) modeling, and machine learning. The main ions included in seawater modify hydration mechanisms, with MgCl2 showing the strongest acceleration effect at the same concentration.
Yanjie Sun   +6 more
wiley   +1 more source

Naringin protects against diabetic cataracts in rats by modulating oxidative stress and inflammation [PDF]

open access: yesArchives of Biological Sciences
This study investigated the efficacy of naringin, a bioflavonoid recognized for its antioxidative and anti-inflammatory properties, in preventing the development of diabetic cataracts.
Meng Gaoqiang, Meng Li, Xu Yalong
doaj   +1 more source

A well‐resolved phylogeny of Cuscuta subgenus Monogynella based on data drawn from all three plant genomes

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Cuscuta (dodders) consists of ~200 species circumscribed into four subgenera (Monogynella, Cuscuta, Pachystigma, and Grammica) and is the only parasitic genus in Convolvulaceae (the morning‐glory family). This group shows a significant diversity in plastid functionality and represents a rare mixotrophic system among parasitic plants ...
Asawari Albal, Saša Stefanović
wiley   +1 more source

Evaluating English translations of ancient Chinese poetry with special reference to image schemas and foregrounding [PDF]

open access: yes
Poetry translation evaluation from ancient Chinese to English has been subjective in China. This is caused by the indefinable and intangible notion of ‘poetic spirit’, which is often used in influential translators’ criteria, and by the lack of a ...
Ye, Mao
core   +2 more sources

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