Results 151 to 160 of about 4,049,704 (295)

A Technique for Patellar Tendon Repair Using a Suture‐Free Nonwoven Polyethylene Terephthalate Implant

open access: yesArthroscopy Techniques, EarlyView.
Abstract Surgical repair remains the standard of care for complete patellar tendon ruptures. However, healing is often challenging due to the tendon's poor biological environment and high tensile stress at the repair site. Bioinductive implants have been introduced to enhance tendon healing; however, they often lack early structural reinforcement. This
McKenzie A. Mayer   +4 more
wiley   +1 more source

Unmet Needs for Ancillary Services by Provider Type Among People With Diagnosed Human Immunodeficiency Virus. [PDF]

open access: yesOpen Forum Infect Dis
Thomas C   +6 more
europepmc   +1 more source

Dynamic pricing of ancillary services based on passenger choice behavior

open access: yes
Based on passenger choice behavior, a dynamic pricing mechanism of ancillary services has been brought up for analysis in this paper. With the analysis of the passenger choice behavior of ancillary services, this study (1) analyzed the pricing of ...
Cheng, Shaoyu, Zhao, Guihong, Cui, Yue
core  

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

Unmet Needs for HIV Ancillary Services Among Persons With Diagnosed HIV Aged 55 years and Older. [PDF]

open access: yesJ Acquir Immune Defic Syndr
Byrd KK   +5 more
europepmc   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton   +8 more
wiley   +1 more source

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