Results 231 to 240 of about 881,645 (296)

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

Advanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang, Ziwen Gao, Hui Huang, Chanyuan Zhang, Yiquan Tang, Qianhui Qu, Huabin Li, Jing Ke, Zhiji Chen, Menglong Feng, Hu Zhou, Yilai Shu, Wei Yuan   +12 more
wiley   +1 more source

West-to-East transmission clusters and meteorological associations for severe hand foot and mouth disease in Shandong Province: a geospatial and GAM analysis. [PDF]

BMC Public Health
Xu X, Wang J, Sun H, Wang Z, Dong Z, Kou Z, Wen H.   +6 more
europepmc   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

Spatio-temporal dynamics of hand, foot and mouth disease in Malaysia, 2009-2019. [PDF]

PLoS Negl Trop Dis
Cox VM, Jahis R, Abu Bakar RS, Yusof NM, Pilay KPV, Chem YK, Selvanesan S, Shamsudin N, Hinsley W, Blake IM, Hasran NZ, Rusli N, Sam IC, Chan YF, Pons-Salort M.   +14 more
europepmc   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

Foot-and-mouth disease in Asia. [PDF]

Virus Res
Rahman MA, Zereen F, Rana ML, Hossain MG, Shimada M, Saha S.   +5 more
europepmc   +1 more source

Active Force Dynamics in Red Blood Cells Under Non‐Invasive Optical Tweezers

Advanced Science, EarlyView.
A non‐invasive method combines low‐power optical tweezers with high‐speed microscopy to simultaneously monitor local membrane forces and displacements in single human red blood cells. This dual‐channel approach reveals a mechano‐dynamic signature that correlates the cell's metabolic state with its mechanical activity. This energetic framework serves as
Arnau Dorn, Clara Luque‐Rioja, Macarena Calero, Diego Herráez‐Aguilar, Francisco Monroy, Niccolò Caselli   +5 more
wiley   +1 more source

Transmission components of hand, foot, and mouth disease in Guangdong Province and their association with meteorological factors: a modelling study. [PDF]

BMC Infect Dis
Tang H, Chen X, Wu Y, Sun J, Chang Y, Chen J, Li J, Lin Y, Liufu Y, Song D, Luo X, Zhang K, Wang Y, Wen Q, Zhang L, Zhang W, Du Z, Hao Y.   +17 more
europepmc   +1 more source

Astragalus Polysaccharide Nanoemulsion: A Promising Adjuvant for Foot-And-Mouth Disease Virus-Like Particle Vaccines. [PDF]

Transbound Emerg Dis
Shi X, Teng Z, Yang K, Song H, Zhang Y, Tan S, Dong H, Sun S, Ding Y, Guo H.   +9 more
europepmc   +1 more source