Results 91 to 100 of about 4,944 (184)

Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6) [PDF]

, 2017
Aims Short QT syndrome (SQTS) is a genetically determined ion-channel disorder, which may cause malignant tachyarrhythmias and sudden cardiac death. Thus far, mutations in five different genes encoding potassium and calcium channel subunits have been ...
Abriel, Hugues, Albesa, Maxime, Antzelevitch, Charles, Barajas-Martinez, Héctor, Baumer, Alessandra, Duru, Firat, Ghadri, Jelena-Rima, Hu, Dan, Kaplan, Vladimir, Lüscher, Thomas F., Puleo, Colleen, Rauch, Anita, Rougier, Jean-Sébastien, Sticht, Heinrich, Templin, Christian   +14 more
core  

Skeletal muscle: molecular structure, myogenesis, biological functions, and diseases

MedComm, Volume 5, Issue 7, July 2024.
The article systematically and comprehensively reviews the physiological and pathological processes associated with skeletal muscles from five perspectives: molecule basis, myogenesis, biological function, poststimulation response, and myopathy. We primarily focus on nuclei‐related behaviors of skeletal muscle, cell–cell fusion, and nuclei migration in
Lan‐Ting Feng, Zhi‐Nan Chen, Huijie Bian   +2 more
wiley   +1 more source

Modulation of Actin Filament Dynamics by Inward Rectifying of Potassium Channel Kir2.1 [PDF]

, 2020
Apart from its ion channel properties, the Kir2.1 channel has been found in tumors and cancer cells to facilitate cancer cell motility. It is assumed that Kir2.1 might be associated with cell actin filament dynamics.
Gu, Junzhong, Gu, Yuchun, Wang, Quanyi, Wu, Lida, Zhang, Huiyuan   +4 more
core   +1 more source

Andersen-Tawil Syndrome with High Risk of Sudden Cardiac Death in Four Mexican Patients. Cardiac and Extra-Cardiac Phenotypes.

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 2020
BACKGROUND Andersen-Tawil syndrome (ATS) is a cardiac channelopathy that is inherited in an autosomal dominant way, and it is characterized by a triad of periodic paralysis, ventricular arrhythmias, and includes some dysmorphic features with incom- plete
David R Barrón-Díaz, Armando Totomoch-Serra, R. E. Escobar-Cedillo, Alan García-Gutierrez, Á. E. Reyes-Quintero, Sergio E Villegas Davirán, Concepción B Ibarra-Miramón, M. Márquez   +7 more
semanticscholar   +1 more source

Tpeak‐Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review

Scientifica, Volume 2024, Issue 1, 2024.
Globally, cardiovascular diseases are still the leading cause of death. Numerous methods are used to diagnose cardiovascular pathologies; there is still a place for straightforward and noninvasive techniques, such as electrocardiogram (ECG). Depolarization and repolarization parameters, including QT interval and its derivatives, are well studied ...
Irena Dykiert, Kamila Florek, Krzysztof Kraik, Paweł Gać, Rafał Poręba, Małgorzata Poręba, Remo Melchio   +6 more
wiley   +1 more source

Local overexpression of the myostatin propeptide increases glucose transporter expression and enhances skeletal muscle glucose disposal [PDF]

, 2014
Insulin resistance (IR) in skeletal muscle is a prerequisite for type 2 diabetes and is often associated with obesity. IR also develops alongside muscle atrophy in older individuals in sarcopenic obesity. The molecular defects that underpin this syndrome
Andersen, D K, Cleasby, M E, Dickson, G, Eilers, W, Elashry, M, Foster, K, Jarmin, S, London, Reading   +8 more
core   +3 more sources

Bidirectional Ventricular Tachycardia: Challenges and Solutions

Vascular Health and Risk Management, 2022
Ahmed Almarzuqi,1 Shane Kimber,1 Kenneth Quadros,1 Janek Senaratne1,2 1Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada; 2Department of Critical Care Medicine, University of ...
Almarzuqi A, Kimber S, Quadros K, Senaratne J   +3 more
doaj  

Up-Regulation of Kir2.1 (KCNJ2) by the Serum & Glucocorticoid Inducible SGK3

Cellular Physiology and Biochemistry, 2014
Background/Aims: The serum & glucocorticoid inducible kinase SGK3, an ubiquitously expressed serine/threonine kinase, regulates a variety of ion channels.
Carlos Munoz, Tatsiana Pakladok, Ahmad Almilaji, Bernat Elvira, Niels Decher, Ekaterina Shumilina, Florian Lang   +6 more
doaj   +1 more source

Nova mutacija kanalčka KCNJ2 pri bolnici s sindromom Andersen-Tawil

Zdravniški Vestnik, 2013
Andersen-Tawil syndrome (ATS) is a rare inherited or sporadic disorder characterized by ventricular arrhythmias, characteristic QT-U wave patterns in electrocardiogram, periodic paralysis, and dysmorphic features.
Matjaž Šinkovec, Andrej Pernat, Matevž Jan, Bor Antolič, Jernej Kovač, Katarina Trebušak Podkrajšek, Maruša Debeljak   +6 more
doaj  

Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1

Frontiers in Physiology, 2015
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are widely used in studying basic mechanisms of cardiac arrhythmias that are caused by ion channelopathies.
Rosalie M.E. Meijer van Putten, Isabella eMengarelli, Kaomei eGuan, Jan G. Zegers, Antoni CG van Ginneken, Arie O Verkerk, Ronald eWilders   +6 more
doaj   +1 more source