Results 71 to 80 of about 860 (142)

Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1

Frontiers in Physiology, 2015
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are widely used in studying basic mechanisms of cardiac arrhythmias that are caused by ion channelopathies.
Rosalie M.E. Meijer van Putten, Isabella eMengarelli, Kaomei eGuan, Jan G. Zegers, Antoni CG van Ginneken, Arie O Verkerk, Ronald eWilders   +6 more
doaj   +1 more source

Polymorphic ventricular tachycardia with mutation in KCNJ2: case report

Frontiers in Cardiovascular Medicine
Polymorphic ventricular tachycardia (VT), particularly in the absence of structural heart disease, has a strong genetic foundation primarily rooted in mutations affecting cardiac ion channels and associated regulatory proteins.
Cuizhen Zhou, Juan Chen, Cuilan Hou, Tingting Xiao, Li Zhang   +4 more
doaj   +1 more source

#51 From Paralysis to Heart Block: A Diagnostic Challenge in Andersen-Tawil Syndrome

Graduate Medical Education Research Journal
Mentor: Jeffrey Robinson Program: Pediatrics – Cardiology Type: Case Report Background: Andersen-Tawil Syndrome (ATS) is a rare genetic disorder caused by mutations in the KCNJ2 gene, which encodes Kir2.1 potassium channels, resulting in the triad of ...
Andrew Nguyen, Danita Velasco, Jeffrey Robinson   +2 more
doaj   +1 more source

Standard Poster Abstracts for the 17th Asia Pacific Heart Rhythm Society (APHRS) Scientific Sessions

Journal of Arrhythmia, Volume 41, Issue 2, April 2025.
wiley   +1 more source

Broad Electrocardiogram Syndromes Spectrum: From Common Emergencies to Particular Electrical Heart Disorders—Part II

Diagnostics
The electrocardiogram (ECG) remains a cornerstone of modern cardiology, providing rapid, non-invasive, and widely accessible diagnostic insights. While ECG interpretation is an essential skill for clinicians, certain patterns can be subtle or atypical ...
Alexandr Ceasovschih, Anastasia Balta, Victorița Șorodoc, Krishnaraj Rathod, Ahmed El Gohary, Serghei Covantsev, Richárd Masszi, Yusuf Ziya Şener, Alexandru Corlăteanu, Syed Haseeb Raza Naqvi, Alexandra Grejdieru, Nicholas G. Kounis, Laurențiu Șorodoc   +12 more
doaj   +1 more source

Paroxysmal limb weakness for ten years

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
DOI: 10.3969/j.issn.1672-6731.2017.07 ...
Meng-yu ZHANG, Yan XU, Jian-zhong SHEN, Yin-chang YANG, Bin PENG, Li-ying CUI   +5 more
doaj  

Atomic-level investigation of KCNJ2 mutations associated with ventricular arrhythmic syndrome phenotypes

Scientific Reports
KCNJ2 encodes the inward rectifying potassium channel (Kir2.1) that underlies I K1 which maintains the cardiac resting membrane potential and regulates excitability.
Saba Munawar, Corey L. Anderson, Louise Reilly, Ryan Woltz, Yusra Sajid Kiani, Nipavan Chiamvimonvat, Lee L. Eckhardt   +6 more
doaj   +1 more source

General anesthesia using propofol infusion for implantation of an implantable cardioverter defibrillator in a pediatric patient with Andersen-Tawil syndrome: a case report. [PDF]

J Dent Anesth Pain Med, 2023
Park S, Heo W, Shin SW, Kim HJ, Yoo YM, Kim HY.   +5 more
europepmc   +1 more source

Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen-Tawil syndrome type 1. [PDF]

Nat Cardiovasc Res, 2022
Macías Á, González-Guerra A, Moreno-Manuel AI, Cruz FM, Gutiérrez LK, García-Quintáns N, Roche-Molina M, Bermúdez-Jiménez F, Andrés V, Vera-Pedrosa ML, Martínez-Carrascoso I, Bernal JA, Jalife J.   +12 more
europepmc   +1 more source

Rare electrocardiographic findings in a young woman with acute barium poisoning: A case report

Heliyon
Background: Barium, as a heavy divalent alkaline earth metal, can be found in various products such as rodenticides, insecticides, depilatories, and fireworks. Barium can be highly toxic upon both acute and chronic exposure.
Yubin Zhang, Xi Huang, Yiru Han, Ren Yan
doaj   +1 more source