Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation [PDF]
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of stroke, heart failure, and death. Fourteen genetic loci have been associated with atrial fibrillation in European and Asian ancestry groups. To further define the
A Deshmukh +197 more
core +9 more sources
Tpeak‐Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review
Globally, cardiovascular diseases are still the leading cause of death. Numerous methods are used to diagnose cardiovascular pathologies; there is still a place for straightforward and noninvasive techniques, such as electrocardiogram (ECG). Depolarization and repolarization parameters, including QT interval and its derivatives, are well studied ...
Irena Dykiert +6 more
wiley +1 more source
Nova mutacija kanalčka KCNJ2 pri bolnici s sindromom Andersen-Tawil
Andersen-Tawil syndrome (ATS) is a rare inherited or sporadic disorder characterized by ventricular arrhythmias, characteristic QT-U wave patterns in electrocardiogram, periodic paralysis, and dysmorphic features.
Matjaž Šinkovec +6 more
doaj
Bidirectional Ventricular Tachycardia: Challenges and Solutions
Ahmed Almarzuqi,1 Shane Kimber,1 Kenneth Quadros,1 Janek Senaratne1,2 1Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada; 2Department of Critical Care Medicine, University of ...
Almarzuqi A +3 more
doaj
Up-Regulation of Kir2.1 (KCNJ2) by the Serum & Glucocorticoid Inducible SGK3
Background/Aims: The serum & glucocorticoid inducible kinase SGK3, an ubiquitously expressed serine/threonine kinase, regulates a variety of ion channels.
Carlos Munoz +6 more
doaj +1 more source
Genome sequence of the stramenopile Blastocystis, a human anaerobic parasite [PDF]
10.1186/gb-2011-12-3-r29Genome ...
France Denoeud +23 more
core +2 more sources
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are widely used in studying basic mechanisms of cardiac arrhythmias that are caused by ion channelopathies.
Rosalie M.E. Meijer van Putten +6 more
doaj +1 more source
In vivo assessment of muscle membrane properties in myotonic dystrophy [PDF]
INTRODUCTION: Myotonia in myotonic dystrophy types 1 (DM1) and 2 (DM2) is generally attributed to reduced chloride channel conductance. We used muscle velocity recovery cycles (MVRCs) to investigate muscle membrane properties in DM1 and DM2, with ...
Bostock, H +5 more
core
The effect of exercise on cardiovascular risk markers in Mexican school-aged children: comparison between two structured group routines [PDF]
Objective. To assess the effects of two groups of exercise routines on cardiovascular disease risk markers. Material and Methods. An intervention study was conducted with 319 Mexican school-aged children in which routines were implemented Monday through ...
BALAS NAKASH, MARGIE +9 more
core
Identification of a PEST Sequence in Vertebrate KIR2.1 That Modifies Rectification
KIR2.1 potassium channels, producing inward rectifier potassium current (IK1), are important for final action potential repolarization and a stable resting membrane potential in excitable cells like cardiomyocytes.
Muge Qile +6 more
doaj +1 more source

