Results 181 to 190 of about 8,677,596 (242)

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, Volume 13, Issue 9, 13 February 2026.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early‐onset sleep disruption in AD‐like amyloidogenic mice

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep–wake disturbances frequently occur at early stages of Alzheimer's disease (AD) and accelerate disease progression, but the underlying neural mechanisms are not fully understood. METHODS We examined sleep–wake behavior and locus coeruleus (LC) activity in young 5xFAD mice using electrophysiology and pharmacological approaches
Yi‐Ci Zhang, Xue‐Ting Zhang, Peng‐Yue Chen, Zi‐Yue Zhou, Mao‐Qing Huang, Kai‐Wen He   +5 more
wiley   +1 more source

Anti-<i>Listeria</i> activity of <i>Lactococcus lactis</i> subsp. <i>lactis</i> LAB3 cells entrapped in alginate beads: effects of inoculum size, alginate bead formulation, and atmosphere composition. [PDF]

Front Microbiol
He Y, Degraeve P, Oulahal N.
europepmc   +1 more source

Effects of Boswellia Serrata and Whey Protein Powders on Physicochemical Properties of Pork Patties. [PDF]

Foods, 2020
Yang F, Cho WY, Lee N, Kim DH, Lee J, Lee HJ, Seo HG, Lee CH.   +7 more
europepmc   +1 more source

Dynamic Gelatin Hydrogels Crosslinked by Dithiolane‐Norbornene Click Chemistry

Macromolecular Bioscience, Volume 26, Issue 2, February 2026.
Gelatin‐norbornene (GelNB) and poly(ethylene glycol)‐tetra‐lipoic acid (PEG4LA) are modularly photo‐crosslinked into gelatin‐based hydrogels with dynamically tunable mechanics for expansion and differentiation of induced pluripotent stem cells (iPSC). ABSTRACT Hydrogels prepared from gelatin are ideal for mimicking the extracellular matrix (ECM) owing ...
Favour O. Afolabi, Lydia Yang He, Chien‐Chi Lin   +2 more
wiley   +1 more source

Effects of Membrane Cholesterol on the Structure and Function of Selected Class A GPCRs─Challenges and Future Perspectives. [PDF]

Biochemistry
Christofidi M, Tzortzini E, Mavromoustakos T, Kolocouris A.   +3 more
europepmc   +1 more source

Differences in Src phosphorylation of PSD‐93 and PSD‐95 drive differences in scaffolding activity

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Scaffold proteins contain multiple binding modules that allow for co‐localization of proteins that lack a direct interaction. Evolution resulted in different combinations of binding modules that rewired existing signal transduction pathways.
Frank A. Mindlin, Moeka Sasazawa, James Byrnes, Mark E. Bowen   +3 more
wiley   +1 more source

Study on Influence Factors of H₂O₂ Generation Efficiency on Both Cathode and Anode in a Diaphragm-Free Bath. [PDF]

Materials (Basel)
Tian T, Wang Z, Li K, Jin H, Tang Y, Sun Y, Wan P, Chen Y.   +7 more
europepmc   +1 more source

The evaluation of protective effect of lycopene against genotoxic influence of X-irradiation in human blood lymphocytes. [PDF]

Radiat Environ Biophys, 2017
Gajowik A, Dobrzyńska MM.
europepmc   +1 more source

A Simple, Ultrastable, and Cost‐Effective Oxygen‐Scavenging System for Long‐Term DNA‐PAINT Imaging

Small, Volume 22, Issue 9, 12 February 2026.
A simple, enzyme‐free, and cost‐effective oxygen scavenging system enhances DNA‐PAINT super‐resolution microscopy by increasing photostability, minimizing docking strand degradation, and enabling faster, high‐precision localizations. Its long‐term stability supports extended imaging, yielding improved spatial resolution and image quality.
Rebecca T. Perelman, George M. Church, Johannes Stein   +2 more
wiley   +1 more source