Results 221 to 230 of about 378,224 (340)

Androgen receptor‐mediated regulation of BRCA1 modulates the antioxidant defense in prostate cancer

The Journal of Pathology, EarlyView.
Abstract Lethal prostate cancer (PCa) is a genetically heterogeneous disease characterized by evolving androgen receptor (AR) signaling, eventually culminating in castration resistance. The tumor suppressor gene BRCA1 has multiple functions that include secondary processes cooperating with its main function as a caretaker of genomic integrity. BRCA1 is
Saiganesh Sriraman, Verneri Virtanen, Antti Kukkula, Mervi Toriseva, Anni Lumiainen, Gun West, Matti Poutanen, Pekka Taimen, Maria Sundvall   +8 more
wiley   +1 more source

Association between CYP17A1 and HSD3B1 gene polymorphisms and testosterone levels in Nigerian prostate cancer patients. [PDF]

Sci Rep
Ekenwaneze CC, Zakari S, Amadi EC, Okesola M, Rotimi SO, Oyekan A, Fatiregun O, Iweala EEJ, Odedina F, Ogunlana OO.   +9 more
europepmc   +1 more source

Receptor Proteins for Androgens

, 1969
Senmaw Fang, K.M. Anderson, Shutsung Liao   +2 more
openalex   +1 more source

Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing

The Journal of Pathology, EarlyView.
Abstract The most common cause of death in pediatric cancer patients is a treatment‐resistant tumor, compounded by metastatic spread, making surgery, radiation therapy, and chemotherapy unfeasible as curative treatment options. However, the mechanisms behind metastatic spread in pediatric tumors remain largely unexplored. We conducted whole‐genome copy
Natalie Andersson, Michele Ferro, Caroline Jansson, Subhayan Chattopadhyay, Jenny Karlsson, David Gisselsson   +5 more
wiley   +1 more source

Identifying 17-β-HSD3 Deficiency in Patients with Karyotype 46,XY Misdiagnosed with Androgen Insensitivity Syndrome: A Pediatric Case Report. [PDF]

Am J Case Rep
Almulhem B, AlJishi FM, Al-Qahtani M.
europepmc   +1 more source

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source

A bibliometric analysis of the effects of sex hormone profiles in women with polycystic ovary syndrome. [PDF]

Medicine (Baltimore)
Li B, Li S, Duan Z, Yu H, Zhou Y, Lin X.
europepmc   +1 more source

Relationship between R m values and protein binding of corticosteroids and androgens [PDF]

, 1973
Ottavio Gandolfi, Anna Barbaro, G. Biagi
openalex   +1 more source

Multiple eumenorrheic cycles are necessary to observe a significant increase in estrogen exposure and ovulation in exercising women with functional hypothalamic oligo/amenorrhea undergoing a nutritional intervention: Insights from the REFUEL study

PM&R, EarlyView.
Abstract Background Due to consequences of energy‐related oligo‐/amenorrhea (Oligo/Amen) among exercising females, recovery of menses (ROM) is a priority. ROM is inconsistently defined and rarely reported with reproductive hormone (estrogen, progesterone) data, making it difficult to know when females achieve adequate recovery. Objective The purpose of
Rebecca J. Mallinson, Nancy I. Williams, Emily A. Ricker, Heather C. M. Allaway, Mary Jane De Souza   +4 more
wiley   +1 more source

A spatiotemporal atlas of orchiectomy-induced androgen deprivation-mediated modulation of cellular composition and gene expression in the mouse prostate. [PDF]

Neoplasia
Shelley G, May A, Robinson T, Dai J, Pitchiaya S, Keller ET.   +5 more
europepmc   +1 more source