Results 1 to 10 of about 141,437 (356)

Androgen Signaling in Uterine Diseases: New Insights and New Targets

Biomolecules, 2022
Common uterine diseases include endometriosis, uterine fibroids, endometrial polyps, endometrial hyperplasia, endometrial cancer, and endometrial dysfunction causing infertility.
Mu Lv, Juanjuan Yu, Yan Huang, Jie Ma, Jun Xiang, Yanqiu Wang, Linxia Li, Zhenbo Zhang, Hong Liao   +8 more
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Contemporary treatment options for male hypogonadism

Journal of Education, Health and Sport, 2023
Introduction Male hypogonadism is a disease in which testicular function is impaired. Its symptoms are due to testosterone deficiency and most of them show low specificity.
Paweł Sojka, Joanna Popiołek, Jakub Szczerba, Szymon Pokora, Agata Stefanowicz, Dominika Pokładnik, Katarzyna Jeleń, Karolina Pokora, Adam Podsiedlik, Alicja Poloczek   +9 more
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Androgens in cervical cancer: Their role in epidemiology and biology

iScience
Summary: This comprehensive review delves into the significance of androgens in cervical cancer, examining both epidemiological evidence and the underlying biological mechanisms.
Yang Gu, Qing Mu, Dali Cheng
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The role of androgens in follicle maturation and ovulation induction: friend or foe of infertility treatment?

Reproductive Biology and Endocrinology, 2011
Background Effects of androgens on follicle maturation have been controversial for some time. Here, we review the potential of their applications in improving human ovulation induction, based on human and animal data, reported in the literature.
Gleicher Norbert, Weghofer Andrea, Barad David H   +2 more
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Hormones and Signaling Pathways Involved in the Stimulation of Leydig Cell Steroidogenesis

Endocrines, 2023
Leydig cells, located in the testis interstitial space, are the primary source of testosterone in males. Testosterone plays critical roles in both reproductive and metabolic functions and therefore is essential for male health.
Karine de Mattos, Kenley Joule Pierre, Jacques J. Tremblay   +2 more
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A Potential Role and Contribution of Androgens in Placental Development and Pregnancy

Life, 2021
Successful pregnancy requires the establishment of a highly regulated maternal–fetal environment. This is achieved through the harmonious regulation of steroid hormones, which modulate both maternal and fetal physiology, and are critical for pregnancy ...
Agata M. Parsons, Gerrit J. Bouma
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Effects of combined GnRHa and letrozole on serum steroid profiles in girls with advanced bone age

Frontiers in Endocrinology
ObjectiveTo evaluate the impact of combined GnRHa and letrozole on serum steroid profiles (classical, 11‐oxygenated, and backdoor androgen pathways) in girls with advanced bone age, and to monitor adverse events.Methods28 girls with advanced bone age ...
Xuan Zhang, Yanan Zhang, Yutong Xing, Wenqing Yang, Yueqiu Qin, Xuehan Gao, Xujing Kong, Susu Cai, Guocui Xue, Xiaomin Fan, Mingzhao Chen, Yongqi Liu, Baorong Chen, Xue Yan, Huifeng Zhang   +14 more
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Circulating adrenal and gonadal steroid hormones heterogeneity in active young males and the contribution of 11-oxy androgens

Scientific Reports
The classical androgens, testosterone and dihydrotestosterone, together with dehydroepiandrosterone, the precusrsor to all androgens, are generally included in diagnostic steroid evaluations of androgen excess and deficiency disorders and monitored in ...
Amanda C. Swart, Desmaré van Rooyen, Therina du Toit, Bianca Heyns, John Molphy, Mathew Wilson, Roisin Leahy, Stephen L. Atkin   +7 more
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Inhibition of Apoptosis in Prostate Cancer Cells by Androgens Is Mediated through Downregulation of c-Jun N-terminal Kinase Activation

Neoplasia: An International Journal for Oncology Research, 2008
Androgen deprivation induces the regression of prostate tumors mainly due to an increase in the apoptosis rate; however, the molecular mechanisms underlying the antiapoptotic actions of androgens are not completely understood.
Petra Isabel Lorenzo, Fahri Saatcioglu
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Androgens and cardiac diseases

Monaldi Archives for Chest Disease, 2013
Although androgens have been considered deleterious for the cardiovascular system, recent data have demonstrated favourable testosterone effects on cardiac and vascular remodeling and clinical outcome.
Vittorio Bianchi, Alessandro Mezzani
doaj   +1 more source