Results 11 to 20 of about 141,437 (356)
Androgens and Androgen Receptor Actions on Bone Health and Disease: From Androgen Deficiency to Androgen Therapy [PDF]
Cells, 2019 Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation therapy ...
Pei-Wen Lin, Hong-Yo Kang, Yi-Ru Tsai
exaly +6 more sources
Androgens and the breast [PDF]
Breast Cancer Research, 2009 Androgens have important physiological effects in women while at the same time they may be implicated in breast cancer pathologies. However, data on the effects of androgens on mammary epithelial proliferation and/or breast cancer incidence are not in ...
Bondy, Carolyn +1 more
core +4 more sources
Androgens and androgen receptors in breast cancer
The Journal of Steroid Biochemistry and Molecular Biology, 2007 Aromatase (CYP19) converts adrenal and ovarian androgens into estrogens, which supports the growth of estrogen-dependent breast cancers. Anti-aromatase agents are displacing antiestrogens as the first-line treatment for estrogen receptor positive breast ...
Chirino Godoy, Ricardo +9 more
core +3 more sources
Androgens and prostate disease
Asian Journal of Andrology, 2014 A growing body of literature has established the anabolic benefi ts of testosterone (T) therapy in hypogonadal men. However, there remains a paucity of data regarding the risks of exogenous androgen use in older men and the potential for adverse effects ...
Lori A Cooper, Stephanie T Page
doaj +2 more sources
Frontiers in Endocrinology, 2023 An increasing number of studies have reported that androgens and androgen receptors (AR) play important roles in the regulation of glucose and lipid metabolism.
Lijun Yin, Shuo Qi, Zhiqiang Zhu
doaj +1 more source
The role of 11-oxygenated androgens in prostate cancer
Endocrine Oncology, 2023 11-oxygenated androgens are a class of steroids capable of activating the androgen receptor (AR) at physiologically relevant concentrations. In view of the AR as a key driver of prostate cancer (PC), these steroids are potential drivers of disease and ...
Gido Snaterse +2 more
doaj +1 more source
Androgens and low density lipoprotein-cholesterol interplay in modulating prostate cancer cell fate and metabolism [PDF]
, 2022 Background: Androgens, the known drivers of prostate cancer (PCa), have been indicated as important metabolic regulators with a relevant role in stimulating lipid metabolism.
Vaz, Cátia V. +6 more
core +1 more source
The Implication of Androgens in the Presence of Protein Kinase C to Repair Alzheimer’s Disease-Induced Cognitive Dysfunction [PDF]
Iranian Biomedical Journal, 2020 Aging, as a major risk factor of memory deficiency, affects neural signaling pathways in hippocampus. In particular, age-dependent androgens deficiency causes cognitive impairments. Several enzymes like PKC are involved in memory deficiency.
Sara Amiri +4 more
doaj +3 more sources
Frontiers in Immunology, 2020 Androgens, the predominant male sex hormones, drive the development and maintenance of male characteristics by binding to androgen receptor (AR). As androgens are systemically distributed throughout the whole organism, they affect many tissues and cell ...
Mireya Becerra-Diaz +2 more
doaj +1 more source
Frontiers in Endocrinology, 2023 ContextRecent evidence support that androgens play an important role in the etiology of endometrial cancer (EC). Adrenal-derived 11-oxygenated androgens are highly potent agonists of the androgen receptor (AR), comparable to testosterone (T) and ...
Cylia Dahmani +7 more
doaj +1 more source