Results 11 to 20 of about 61,244 (265)
Androgen regulation of the androgen receptor coregulators [PDF]
BMC Cancer, 2008 Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso +4 more
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Androgens’ effects on cerebrovascular function in health and disease
Biology of Sex Differences, 2020 Androgens affect the cerebral vasculature and may contribute to sex differences in cerebrovascular diseases. Men are at a greater risk for stroke and vascular contributions to cognitive impairment and dementia (VCID) compared to women throughout much of ...
Charly Abi-Ghanem +2 more
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Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors. [PDF]
PLoS ONE, 2012 Prostate cancer (PCa) is the second most common cancer in men. Androgen deprivation therapy (ADT) leads to tumor involution and reduction of tumor burden.
Elahe A Mostaghel +4 more
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Estrogens and Androgens in Plants: The Last 20 Years of Studies
Plants, 2021 Although the only known steroid hormones in plants are brassinosteroids, interestingly, mammalian steroid hormones such as androgens or estrogens are also part of the plant metabolic profile. This presented review is focused on the progress that has been
Anna Janeczko
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ANDROGENS REGULATE T47D CELLS MOTILITY AND INVASION THROUGH ACTIN CYTOSKELETON REMODELLING
Frontiers in Endocrinology, 2016 The relationship between androgens and breast cancer is controversial. Androgens have complex effects on breast cancer progression and metastasis. Moreover, androgens receptor (AR) is expressed in approximately 70% to 90% of invasive breast carcinomas ...
Maria Magdalena Montt-Guevara +7 more
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Biomolecules, 2022 Androgens are steroids that modulate various processes in the body, ranging from reproduction, metabolism, and even immune response. The main androgens are testosterone, dihydrotestosterone (DHT) and dehydroepiandrosterone (DHEA). These steroids modulate
Fidel Orlando Buendía-González +1 more
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American Journal of Men's Health, 2011 Many theories aim at explaining the mechanisms of aging and death in humans. Decreased levels of androgens, growth hormone, and insulin-like growth factor accompany natural aging in men.
Genovefa Kolovou MD, PhD +3 more
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PLoS ONE, 2016 Gastropod mollusks have been proposed as alternative models for male reproductive toxicity testing, due to similarities in their reproductive anatomy compared to mammals, together with evidence that endocrine disrupting chemicals can cause effects in ...
Satwant Kaur +6 more
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Ornithine Decarboxylase Activity Is Required for Prostatic Budding in the Developing Mouse Prostate. [PDF]
PLoS ONE, 2015 The prostate is a male accessory sex gland that produces secretions in seminal fluid to facilitate fertilization. Prostate secretory function is dependent on androgens, although the mechanism by which androgens exert their effects is still unclear ...
Melissa Gamat +4 more
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Frontiers in Endocrinology, 2022 High concentrations of glucocorticoids caused by chronic stress are known to affect ovarian function and cause diminished ovarian reserve. Androgens are essential for early-stage ovarian follicle development, but the effects and mechanisms of androgens ...
Lingyun Gao +5 more
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