Results 1 to 10 of about 75,567 (147)

The multiple actions of testosterone in men: nature knows best

Asian Journal of Andrology, 2014
In male hormone replacement therapy Finkelstein et al. show that testosterone rather than synthetic "pure" androgens should be prescribed. Testosterone is converted to the superactive androgen dihydrotestosterone and to estradiol, and thus has actions ...
John W Funder
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Androgen receptor abnormalities [PDF]

The Journal of Steroid Biochemistry and Molecular Biology, 1991
The human androgen receptor is a member of the superfamily of steroid hormone receptors. Proper functioning of this protein is a prerequisite for normal male sexual differentiation and development. The cloning of the human androgen receptor cDNA and the elucidation of the genomic organization of the corresponding gene has enabled us to study androgen ...
Brinkmann, A. O., Kuiper, G. G., Ris-Stalpers, C., van Rooij, H. C., Romalo, G., Trifiro, M., Mulder, E., Pinsky, L., Schweikert, H. U., Trapman, J.   +9 more
openaire   +2 more sources

A study of the prostate, androgens and sexual activity of male rats

Reproductive Biology and Endocrinology, 2007
Background The prostate is a sexual gland that produces important substances for the potency of sperm to fertilize eggs within the female reproductive tract, and is under complex endocrine control.
Garcia Luis I, Rojas Fausto, Díaz Rosaura, Aranda-Abreu Gonzalo E, Soto-Cid Abraham, Hernandez Maria, Toledo Rebeca, Manzo Jorge   +7 more
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Integrins and Actions of Androgen in Breast Cancer

Cells, 2023
Androgen has been shown to regulate male physiological activities and cancer proliferation. It is used to antagonize estrogen-induced proliferative effects in breast cancer cells. However, evidence indicates that androgen can stimulate cancer cell growth
Chung-Che Tsai, Yu-Chen S. H. Yang, Yi-Fong Chen, Lin-Yi Huang, Yung-Ning Yang, Sheng-Yang Lee, Wen-Long Wang, Hsin-Lun Lee, Jacqueline Whang-Peng, Hung-Yun Lin, Kuan Wang   +10 more
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Clinical and morphological features of peptic ulcer at men and women [PDF]

Саратовский научно-медицинский журнал, 2010
The aim of research was to study clinical and morphological features of peptic ulcer at men and women of various age. 166 patients with duodenal peptic ulcer (80 men and 86 women) and 138 with stomach peptic ulcer (80 men and 58 women) were inspected ...
Islamova Е.А., Lipatova Т.Е.
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Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors

Brazilian Oral Research, 2009
The aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands ...
Fabio Augusto Ito, Kazuhiro Ito, Ricardo Della Coletta, Pablo Agustín Vargas, Márcio Ajudarte Lopes   +4 more
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The epigenetic function of androgen receptor in prostate cancer progression

Frontiers in Cell and Developmental Biology, 2023
Androgen and androgen deprivation (castration) therapies, including androgen receptor antagonists, are clinically used to treat patients with prostate cancer.
Takahiro Sawada, Takahiro Sawada, Yoshiaki Kanemoto, Yoshiaki Kanemoto, Tomohiro Kurokawa, Tomohiro Kurokawa, Tomohiro Kurokawa, Shigeaki Kato, Shigeaki Kato, Shigeaki Kato   +9 more
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Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway

Frontiers in Pharmacology
BackgroundPulmonary arterial hypertension (PAH) exhibits significant gender differences in prognosis, with male patients typically showing worse outcomes than females.
Jiayan Sun, Jiayan Sun, Jiayan Sun, Jiancheng Lin, Jiancheng Lin, Jiancheng Lin, Di Yin, Di Yin, Di Yin, Zetao Pan, Zetao Pan, Zetao Pan, Yuheng Ye, Yuheng Ye, Yuheng Ye, Yi Wang, Yi Wang, Yi Wang, Xiaowan Wang, Xiaowan Wang, Xiaowan Wang, Qiang Guo, Qiang Guo, Qiang Guo, Qiang Guo   +24 more
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The roles of sex steroid receptor coregulators in cancer

Molecular Cancer, 2002
Sex steroid hormones, estrogen, progesterone and androgen, play pivotal roles in sex differentiation and development, and in reproductive functions and sexual behavior.
Loggie Brian W, Gao Xiuhua, Nawaz Zafar
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Androgen receptors as a prognostic and predictive factor in breast cancer.

Folia Histochemica et Cytobiologica, 2008
Many theoretical and experimental models indicate that androgen receptors can play an important role as prognostic factors in breast cancer. The aim of this study was to evaluate the correlations between the presence of androgen receptors on cancer cells
Jerzy Rudnicki, Piotr Zukrowski, Zygmunt Grzebieniak, Michał Jeleń, Anil K Agrawal, Ewa Nienartowicz   +5 more
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