Results 41 to 50 of about 75,567 (147)
The androgen/androgen receptor axis in prostate cancer [PDF]
Current Opinion in Oncology, 2012 The review highlights recently discovered mechanisms that sustain castration-resistant prostate cancer (CRPC) growth and describes advances in CRPC therapeutics.Recent reports have shed new light on the molecular processes underlying CRPC survival during androgen deprivation therapy (ADT).
Eric G, Bluemn, Peter S, Nelson
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Could Testosterone Have a Therapeutic Role in Prostate Cancer?
Urology Journal, 2013 PURPOSE:To discuss the role of membrane androgen receptors and to investigate the potential role of testosterone-albumin conjugate in the prostate cancer (PCa) treatment.MATERIALS AND METHODS: We identified studies published from 1990 onwards by ...
Konstantinos Stamatiou
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Prostate cancer and therapeutic challenges
Journal of Biological Research - Thessaloniki, 2020 Prostate cancer (PC) is the most prevalent type of cancer in men worldwide. In Saudi Arabia, the rate of PC is increasing annually. The sex steroid hormones androgens and their receptors have critical roles in PC development and progression. Additionally,
Yousef MohammedRabaa Hawsawi +5 more
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Expression of Androgen Receptor in Human Placentas from Normal and Preeclamptic Pregnancies
Taiwanese Journal of Obstetrics & Gynecology, 2009 Objective: To elucidate the expression of androgen receptor (AR) in human placenta from normal and preeclamptic (PE) pregnancies. Materials and Methods: This study was performed at the Division of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial ...
Te-Yao Hsu +9 more
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Pre-receptor regulation of the androgen receptor [PDF]
Molecular and Cellular Endocrinology, 2008 The human androgen receptor (AR) is a ligand-activated nuclear transcription factor and mediates the induction of genes involved in the development of the male phenotype and male secondary sex characteristics, as well as the normal and abnormal growth of the prostate.
Trevor M, Penning +3 more
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Androgen receptor epigenetics.
Translational andrology and urology, 2013 The androgen receptor (AR) is a transcription factor that drives the differentiation of prostate epithelium by regulating the expression of several hundred genes. Conversely, AR also plays a central role in prostate cancer (PCa) development, and it continues to be active in tumors that relapse after castration (castration-resistant prostate cancer ...
Cai, Changmeng +2 more
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Basic & Clinical Cancer Research, 2016 Background: Androgen receptors (AR) play an important role in proliferation of cancerous prostatic cells and prevention of apoptotic signaling. Current drugs cannot inhibit the activity of these receptors very well.
Samad Muhammadnejad +6 more
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İstanbul Kuzey Klinikleri, 2019 INTRODUCTION[|]Androgen (AR), Estrogen (ER) and Progesterone (PR) hormones play an important role in the prenatal and postnatal development of urogenital tract and especially the penis.
Ayşenur Celayir +4 more
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A study of androgen and estrogen receptors α, β in skin tags
Indian Journal of Dermatology, 2010 Background: In women, the age of 50 is suggested to be the turning point of life at which the development of skin tags comes to a stop. A major event that occurs around this period of life is menopause/andropause.
El Safoury Omar +2 more
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Androgens and the androgen receptor (AR)
, 2013 Introduction Androgens are sex steroid hormones that are produced in both males and females, albeit in different amounts. Androgens are essential for development and maintenance of the male phenotype (1), and are also important in females, where they can either act directly via the androgen receptor (AR) or indirectly as metabolic precursors for ...
Moore, N. +4 more
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