Results 51 to 60 of about 75,567 (147)

The Androgen Receptor in Breast Cancer

open access: yesFrontiers in Endocrinology, 2018
Breast cancer (BC) is a hormone-related tumor. Despite the progress in BC therapy, this disease still remains the most common cancer amongst women around the world. This is likely due to the amazing BC heterogeneity. Accumulating evidence suggests a role for androgen signaling in BC.
Giovannelli, Pia   +5 more
openaire   +4 more sources

Sex Hormones and Their Receptors Regulate Liver Energy Homeostasis

open access: yesInternational Journal of Endocrinology, 2015
The liver is one of the most essential organs involved in the regulation of energy homeostasis. Hepatic steatosis, a major manifestation of metabolic syndrome, is associated with imbalance between lipid formation and breakdown, glucose production and ...
Minqian Shen, Haifei Shi
doaj   +1 more source

Correlation between the number of breast duct cells expressing androgen, estrogen and progesterone receptors and the size of the changed tissue in patients with gynecomastia [PDF]

open access: yesMedicinski Podmladak, 2023
Introduction: Gynecomastia is an abnormal growth of the male breast due to excessive proliferation of ductal epithelial cells. It usually occurs during puberty, so the influence of hormones on the stimulation of ductal cells is indicative.
Mladenović Danilo   +2 more
doaj  

N-acetylcysteine and zinc sulphate abate di-2-ethylhexyl phthalate-mediated reproductive dysfunction in rats: Focus on oxidative and sex hormone receptors mechanisms

open access: yesAsian Pacific Journal of Reproduction
Objective: To investigate the potential of N-acetylcysteine (NAC) and zinc sulphate (ZnSO4) in mitigating reproductive dysfunction caused by di-2-ethylhexyl phthalate (DEHP) in rats and to understand the underlying mechanisms, specifically oxidative ...
Victor Oghenekparobo Emojevwe   +9 more
doaj   +1 more source

The impacts of gender differences on systemic lupus erythematosus and lupus nephritis

open access: yesLinchuang shenzangbing zazhi, 2019
Systemic lupus erythematosus is a common autoimmune disease,and lupus nephritis is one of its common complications. Their clinical manifestations have differences. The incidence ratio of male to female varies by age group.
LI Chun-hong, TIAN Jie
doaj  

Hormone Receptors in Cervicovaginal Cells

open access: yesGynecology Obstetrics & Reproductive Medicine, 2013
Some parts of the female reproductive system such as vagina and ectocervix is covered with stratified squamous epithelium (SSE). SSE consists of many layers and steroid hormones are essential for its normal growth and development.
Şayeste Demirezen   +2 more
doaj  

Androgens and Androgen Receptor Actions on Bone Health and Disease: From Androgen Deficiency to Androgen Therapy

open access: yesCells, 2019
Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation therapy ...
Jia-Feng Chen   +4 more
doaj   +1 more source

A concise review of testosterone and bone health

open access: yesClinical Interventions in Aging, 2016
Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman, Kok-Yong Chin Department of Pharmacology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lampur, Malaysia Abstract: Osteoporosis is a condition causing significant morbidity and mortality in the elderly
Mohamad NV, Soelaiman IN, Chin KY
doaj  

Kaempferol Promotes Apoptosis While Inhibiting Cell Proliferation via Androgen-Dependent Pathway and Suppressing Vasculogenic Mimicry and Invasion in Prostate Cancer

open access: yesAnalytical Cellular Pathology, 2019
Kaempferol is a well-known natural flavonol reported to be a potential treatment for multiple cancers. In this study, we demonstrated that cell growth of androgen-sensitive LNCaP cells could be inhibited 33% by 5 μM kaempferol, around 60% by 10 μM ...
Jun Da   +5 more
doaj   +1 more source

Molecular Defects of the Androgen Receptor

open access: yesRecent Progress in Hormone Research, 1999
Defects of the androgen receptor cause a wide spectrum of abnormalities of phenotypic male development, ranging from individuals with mild defects of virilization to those with complete female phenotypes. In parallel with this phenotypic spectrum, a large number of different mutations have been identified that alter the synthesis or functional activity
openaire   +3 more sources

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