Results 1 to 10 of about 78,518 (314)

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen. [PDF]

PLoS ONE, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Peter J O'Shaughnessy, Ana Monteiro, Margaret Abel   +2 more
doaj   +3 more sources

Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus

Acta Dermato-Venereologica, 2018
Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng, Yun-Long Cheng, Chuan-Chuan Cai, Ya-Yun Wu, Ge Shi, Ying Zhou, Yi-Ming Fan   +6 more
doaj   +2 more sources

Androgen receptor expression in hypospadias

Journal of Indian Association of Pediatric Surgeons, 2020
Introduction: The exact mechanism behind the development of hypospadias is unclear. Research studies on androgen receptor (AR) expression are controversial with results stating all possible outcomes – AR elevated, similar, or reduced when compared to ...
Dhanvanth Rajesh Balaji, Goutham Reddy, Ramesh Babu, Balamourougane Paramaswamy, Madhu Ramasundaram, Prakash Agarwal, Leena Dennis Joseph, Lawrence D'Cruze, Sandhya Sundaram   +8 more
doaj   +3 more sources

Androgens and Androgen Receptor Actions on Bone Health and Disease: From Androgen Deficiency to Androgen Therapy

Cells, 2019
Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation therapy ...
Jia-Feng Chen, Pei-Wen Lin, Yi-Ru Tsai, Yi-Chien Yang, Hong-Yo Kang   +4 more
doaj   +2 more sources

Prognostic Value of Androgen Receptor Expression in Bladder Tumors [PDF]

Translational Research in Urology, 2023
Introduction: The present study was conducted with the aim of investigating the prognostic value of androgen receptor expression in bladder tumors.Methods: This study was conducted in the urology department of Imam Reza Hospital on male patients with ...
Salman Soltani, Sajjad Sadeghpour, Mahmood Reza Kalantari, Hamidreza Ghorbani, Majid Khadem Rezaiyan, Atena Aghaee, Mahmoud Tavakoli, Hamideh Heydari, Samira Assarian   +8 more
doaj   +1 more source

Binding of Androgen- and Estrogen-Like Flavonoids to Their Cognate (Non)Nuclear Receptors: A Comparison by Computational Prediction

Molecules, 2021
Flavonoids are plant bioactives that are recognized as hormone-like polyphenols because of their similarity to the endogenous sex steroids 17β-estradiol and testosterone, and to their estrogen- and androgen-like activity. Most efforts to verify flavonoid
Giulia D’Arrigo, Eleonora Gianquinto, Giulia Rossetti, Gabriele Cruciani, Stefano Lorenzetti, Francesca Spyrakis   +5 more
doaj   +1 more source

Androgen regulation of the androgen receptor coregulators [PDF]

BMC Cancer, 2008
Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso, Waltering, Kati K, Suikki, Hanna E, Helenius, Merja A, Visakorpi, Tapio   +4 more
openaire   +4 more sources

Androgen receptor mutations [PDF]

The Journal of Steroid Biochemistry and Molecular Biology, 1995
Male sexual differentiation and development proceed under direct control of androgens. Androgen action is mediated by the intracellular androgen receptor, which belongs to the superfamily of ligand-dependent transcription factors. At least three pathological situations are associated with abnormal androgen receptor structure and function: androgen ...
Brinkmann, A. O., Jenster, G., Ris-Stalpers, C., van der Korput, J. A., Brüggenwirth, H. T., Boehmer, A. L., Trapman, J.   +6 more
openaire   +3 more sources

Androgen and Estrogen Receptor Expression in Different Types of Perianal Gland Tumors in Male Dogs

Animals, 2021
Perianal gland tumors are modified sebaceous glands present in the skin of the perianal region in the dog. Hormonal stimulation may induce hyperplasia of the perianal glands or their neoplastic progression. The presence of androgen (AR) and estrogen (ER)
Adam Brodzki, Wojciech Łopuszyński, Yolanda Millan, Marcin R. Tatara, Piotr Brodzki, Katarzyna Kulpa, Natalia Minakow   +6 more
doaj   +1 more source

Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma

Zhongliu Fangzhi Yanjiu, 2023
Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1.
WANG Ruihua, CAI Shiliang, LIU Donghong, CHEN Hongsen, CAO Guangwen   +4 more
doaj   +1 more source