The multiple actions of testosterone in men: nature knows best
Asian Journal of Andrology, 2014 In male hormone replacement therapy Finkelstein et al. show that testosterone rather than synthetic "pure" androgens should be prescribed. Testosterone is converted to the superactive androgen dihydrotestosterone and to estradiol, and thus has actions ...
John W Funder
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DRUG THERAPY FOR ANDROGEN-POSITIVE BREAST CANCER
Сибирский онкологический журнал, 2021 There are some types of breast cancer (BC) that depend on their molecular characteristics. However, lately researchers provide date regarding the presence of additional receptors of triple negative breast cancer (TNBC).
A. D. Zikiryakhodjhaev +4 more
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The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium [PDF]
, 2008 Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation.
Cartwright, JE +44 more
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Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function [PDF]
, 2014 This work was supported by grants from the NIH (R01CA86072 to R.G.P. and R01CA72038-01 to S.A.W.F.) and The Susan Komen Breast Cancer Foundation (to R.G.P.). R.T.H. and E.J. were supported by the Medical Research Council. Y.-G.Y.
Wang, Jian +13 more
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A study of the prostate, androgens and sexual activity of male rats
Reproductive Biology and Endocrinology, 2007 Background The prostate is a sexual gland that produces important substances for the potency of sperm to fertilize eggs within the female reproductive tract, and is under complex endocrine control.
Garcia Luis I +7 more
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Clinical and morphological features of peptic ulcer at men and women [PDF]
Саратовский научно-медицинский журнал, 2010 The aim of research was to study clinical and morphological features of peptic ulcer at men and women of various age. 166 patients with duodenal peptic ulcer (80 men and 86 women) and 138 with stomach peptic ulcer (80 men and 58 women) were inspected ...
Islamova Е.А., Lipatova Т.Е.
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Integrins and Actions of Androgen in Breast Cancer
Cells, 2023 Androgen has been shown to regulate male physiological activities and cancer proliferation. It is used to antagonize estrogen-induced proliferative effects in breast cancer cells. However, evidence indicates that androgen can stimulate cancer cell growth
Chung-Che Tsai +10 more
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Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]
, 2010 Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Hu, Z.Y. +7 more
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Transcriptional regulation of prostate kallikrein-like genes by androgen. [PDF]
, 1992 Using gene-specific synthetic oligonucleotides the expression and regulation of kallikrein-like genes in the human prostatic cancer cell line LNCaP were studied.
Schulz, Peter +2 more
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Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
Brazilian Oral Research, 2009 The aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands ...
Fabio Augusto Ito +4 more
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