Results 51 to 60 of about 78,719 (215)
Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats [PDF]
, 2012 We investigated the effects of different windows of testosterone propionate (TP) treatment during foetal and neonatal life in female rats to determine whether and when excess androgen exposure would cause disruption of adult reproductive function ...
Alan S McNeilly +17 more
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Androgen Receptors in Human Breast Cancer and Female Canine Mammary Tumors
MoleculesThis review explores the potential role of androgens in human breast cancer and female canine mammary tumors. Human breast cancer is one of the most common cancers affecting women globally, while female canine mammary tumors provide a natural model for ...
Vladimir Vidović +5 more
doaj +1 more source
Insights into Androgen Receptor Action in Lung Cancer
Endocrines, 2023 Sex hormones and their receptors play a crucial role in human sexual dimorphism and have been traditionally associated with hormone-dependent cancers like breast, prostate, and endometrial cancer.
Darko Durovski +2 more
doaj +1 more source
Androgen-induced migration in NIH3T3 mouse fibroblasts: role of AR association with Filamin A. [PDF]
, 2010 Androgen stimulation triggers rapid activation of various signaling effectors in target cells (Migliaccio et al. 2000; Castoria et al. 2003). This occurs through a direct interaction of classical steroid receptors with proto-oncogenic tyrosine kinase ...
Giraldi, Tiziana
core
Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes [PDF]
, 2014 Communication between organs and tissues is predominately controlled by hormones. Hormones regulate a vast variety of physiological and behavioural activities, including metabolism, growth and development, reproduction, sleep and mood.
Fürstenberger, Cornelia
core +1 more source
Proteomic changes in rat spermatogenesis in response to in vivo androgen manipulation; impact on meiotic cells. [PDF]
PLoS ONE, 2012 The production of mature sperm is reliant on androgen action within the testis, and it is well established that androgens act on receptors within the somatic Sertoli cells to stimulate male germ cell development.
Peter G Stanton +6 more
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Frontiers in Endocrinology, 2023 BackgroundKlinefelter’s syndrome (KS) was once considered infertile due to congenital chromosomal abnormalities, but the presence of focal spermatozoa changed this.
Huang Liu +12 more
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Reproductive Biology and EndocrinologyGonadal steroids are involved in the organization and programming of several neural systems. The main objective of this study was to determine whether androgen activity in the early postnatal stage influenced the long-term expression of androgen and ...
Rocío García-Úbeda +8 more
doaj +1 more source
ARD1/NAA10 acetylation in prostate cancer
Experimental and Molecular Medicine, 2018 Prostate cancer: Preventing androgen receptor activation Blocking the addition of an acetyl group to androgen receptors by Arrest-defect-1 protein (ARD1) might be an effective strategy for halting prostate cancer progression.
Katherine J. Kuhns +3 more
doaj +1 more source
Lipid Metabolic Disorders in Neurodegenerative Diseases – Role of Androgen Receptor
Eurasian Journal of Medicine, 2023 The challenge of managing neurodegenerative disorders is a worldwide concern, especially in the aging population. Neurodegenerative diseases are a varied group of disorders that are characterized by progressive degeneration of the structure and function
Satvika Sharma +2 more
doaj +1 more source