Results 21 to 30 of about 73,737 (266)

A computational insight into endocrine disruption by polychlorinated biphenyls via non-covalent interactions with human nuclear receptors

open access: yesEcotoxicology and Environmental Safety, 2021
Production of polychlorinated biphenyls (PCBs) was banned a long time ago because of their harmful health effects but humans continue to be exposed to residual PCBs in the environment.
Lukman K. Akinola   +3 more
doaj   +1 more source

Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells

open access: yesMolecular Cancer, 2008
Background Recently we have reported membrane androgen receptors-induced apoptotic regression of prostate cancer cells regulated by Rho/ROCK/actin signaling.
Gravanis Achilleas   +8 more
doaj   +1 more source

DRUG THERAPY FOR ANDROGEN-POSITIVE BREAST CANCER

open access: yesСибирский онкологический журнал, 2021
There are some types of breast cancer (BC) that depend on their molecular characteristics. However, lately researchers provide date regarding the presence of additional receptors of triple negative breast cancer (TNBC).
A. D. Zikiryakhodjhaev   +4 more
doaj   +1 more source

Adiponectin and its receptors in the ovary: further evidence for a link between obesity and hyperandrogenism in polycystic ovary syndrome. [PDF]

open access: yesPLoS ONE, 2013
Polycystic ovary syndrome (PCOS), characterized by ovarian androgen excess, is the commonest endocrine disorder in women. Obesity increases androgen synthesis, a phenomenon attributed to the accompanying hyperinsulinemia.
Fabio V Comim   +2 more
doaj   +1 more source

The multiple actions of testosterone in men: nature knows best

open access: yesAsian Journal of Andrology, 2014
In male hormone replacement therapy Finkelstein et al. show that testosterone rather than synthetic "pure" androgens should be prescribed. Testosterone is converted to the superactive androgen dihydrotestosterone and to estradiol, and thus has actions ...
John W Funder
doaj   +1 more source

A study of the prostate, androgens and sexual activity of male rats

open access: yesReproductive Biology and Endocrinology, 2007
Background The prostate is a sexual gland that produces important substances for the potency of sperm to fertilize eggs within the female reproductive tract, and is under complex endocrine control.
Garcia Luis I   +7 more
doaj   +1 more source

Integrins and Actions of Androgen in Breast Cancer

open access: yesCells, 2023
Androgen has been shown to regulate male physiological activities and cancer proliferation. It is used to antagonize estrogen-induced proliferative effects in breast cancer cells. However, evidence indicates that androgen can stimulate cancer cell growth
Chung-Che Tsai   +10 more
doaj   +1 more source

Clinical and morphological features of peptic ulcer at men and women [PDF]

open access: yesСаратовский научно-медицинский журнал, 2010
The aim of research was to study clinical and morphological features of peptic ulcer at men and women of various age. 166 patients with duodenal peptic ulcer (80 men and 86 women) and 138 with stomach peptic ulcer (80 men and 58 women) were inspected ...
Islamova Е.А., Lipatova Т.Е.
doaj  

Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors

open access: yesBrazilian Oral Research, 2009
The aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands ...
Fabio Augusto Ito   +4 more
doaj   +1 more source

The epigenetic function of androgen receptor in prostate cancer progression

open access: yesFrontiers in Cell and Developmental Biology, 2023
Androgen and androgen deprivation (castration) therapies, including androgen receptor antagonists, are clinically used to treat patients with prostate cancer.
Takahiro Sawada   +9 more
doaj   +1 more source

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