ContextRecent evidence support that androgens play an important role in the etiology of endometrial cancer (EC). Adrenal-derived 11-oxygenated androgens are highly potent agonists of the androgen receptor (AR), comparable to testosterone (T) and ...
Cylia Dahmani +7 more
doaj +1 more source
The Implication of Androgens in the Presence of Protein Kinase C to Repair Alzheimer’s Disease-Induced Cognitive Dysfunction [PDF]
Aging, as a major risk factor of memory deficiency, affects neural signaling pathways in hippocampus. In particular, age-dependent androgens deficiency causes cognitive impairments. Several enzymes like PKC are involved in memory deficiency.
Sara Amiri +4 more
doaj +1 more source
Association between prenatal androgens and cord blood androgens, a path analysis
To determine association paths between prenatal androgens and cord blood androgens. The concentrations of T, FT, DHT, DHEA and SHBG in prenatal venous blood and cord blood were measured in 342 pregnant women and their neonates.
Hui Xu +9 more
doaj +1 more source
Profiling of androgen response in rainbow trout pubertal testis: relevance to male gonad development and spermatogenesis. [PDF]
The capacity of testicular somatic cells to promote and sustain germ cell differentiation is largely regulated by sexual steroids and notably androgens. In fish species the importance of androgens is emphasized by their ability to induce sex reversal of ...
Antoine D Rolland +6 more
doaj +1 more source
Androgens, Endometriosis and Pain
The intriguing relationship between androgens, endometriosis and chronic pain continues to unfold. Determining this relationship is of crucial importance to gynecologists managing people with these conditions, as common treatments dramatically alter her ...
Susan F. Evans +5 more
doaj +1 more source
Attenuated androgen discontinuation in patients with hereditary angioedema: a commented case series
Background Hereditary angioedema (HAE) is characterized by potentially severe and life-threatening attacks of localized swelling. Prophylactic therapies are available, including attenuated androgens. Efficacy of attenuated androgens has not been assessed
Marcus Maurer +11 more
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Androgen regulation of the androgen receptor coregulators [PDF]
Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso +4 more
openaire +4 more sources
Androgens’ effects on cerebrovascular function in health and disease
Androgens affect the cerebral vasculature and may contribute to sex differences in cerebrovascular diseases. Men are at a greater risk for stroke and vascular contributions to cognitive impairment and dementia (VCID) compared to women throughout much of ...
Charly Abi-Ghanem +2 more
doaj +1 more source
Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors. [PDF]
Prostate cancer (PCa) is the second most common cancer in men. Androgen deprivation therapy (ADT) leads to tumor involution and reduction of tumor burden.
Elahe A Mostaghel +4 more
doaj +1 more source
Estrogens and Androgens in Plants: The Last 20 Years of Studies
Although the only known steroid hormones in plants are brassinosteroids, interestingly, mammalian steroid hormones such as androgens or estrogens are also part of the plant metabolic profile. This presented review is focused on the progress that has been
Anna Janeczko
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