The impact of short-term non-steroidal androgen antagonist therapy on PSMA expression and tumor cellularity studied with dynamic [<sup>68</sup>Ga]Ga-PSMA-11 PET/MR in hormone-sensitive prostate cancer patients, a preliminary longitudinal prospective study. [PDF]
Sanchez-Crespo A+6 more
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Read the free Plain Language Summary for this article on the Journal blog. Abstract Phenotypic plasticity is a strategy by which animals alter behaviour, morphology and/or physiology in response to cues of current conditions to cope with environmental heterogeneity.
Lauren Petrullo+3 more
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An anti-androgen resistance-related gene signature acts as a prognostic marker and increases enzalutamide efficacy via PLK1 inhibition in prostate cancer. [PDF]
Han Y, Xie W, Wu G, Wu G.
europepmc +1 more source
Considerations of Fertility in Elite Sportswomen: A Narrative Review
ABSTRACT Background Increasingly more women are participating in professional and recreational sports. Whilst vigorous intensity physical activity is considered beneficial, evidence demonstrates higher rates of menstrual disturbance in elite athletes. There is less clear evidence on the impact of elite‐level exercise on fertility outcomes.
Ariadne L'Heveder+11 more
wiley +1 more source
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel+5 more
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A review of exercise-induced epigenetic modifications in prostate tissue: implications for gene expression and tumor progression in prostate cancer. [PDF]
Ye K, Ke Z, Gesang W, Liang K, Malek M.
europepmc +1 more source
Epigenetic Clock Analysis of Sex Chromosome Aneuploidies
Next‐generation epigenetic clocks indicate lower age acceleration and slower pace of aging in 47,XXY than 46,XX, 46,XY, and 47,XYY. A first‐generation clock (Skin & Blood) indicates higher age acceleration in 47,XXY and 47,XYY than 46,XY, while higher naïve CD8+ T in 47,XXY than both 46,XY and 46,XX suggests reduced immunosenescence.
Joshua Zhang+7 more
wiley +1 more source
Abstract Background Opioid use disorder (OUD) imposes a significant socioeconomic burden, highlighting the need for new interventions. Objective This study investigated whether exposure to 5‐alpha reductase inhibitors (5αRIs) is associated with a lower risk of developing OUD.
Abdelrahman G. Tawfik+5 more
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Correction: Androgen receptor signaling induces hemorrhage and angiogenesis in the irradiated bladder. [PDF]
Komori T+6 more
europepmc +1 more source
Breast and Nipple Dermatoses During Lactation
ABSTRACT Lactation and breastfeeding can present both psychological and physical challenges for breastfeeding mothers. In addition, many nursing mothers will also suffer from breast and nipple dermatoses during this period, compounding these difficulties. Common causes of breast and nipple dermatitis during lactation include eczema, psoriasis, mastitis,
Hamish Moore, Annabel Stevenson
wiley +1 more source