Results 91 to 100 of about 30,274 (252)
"Mixed germ cell testicular tumor" in an adult female
The androgen insensitivity (testicular feminization) syndrome was described by Morris in phenotypic females with 46XY karyotype, presenting with primary amenorrhea, adequate breast development, and absent or scanty pubic or axillary hair.
Udasimath Shivakumarswamy+3 more
doaj +1 more source
Optimizing care for MRKH patients: From malformation screening to uterus transplantation eligibility
38% of women with MRKH syndrome are inadequately explored for associated malformations. Early assessment of ovarian reserve is necessary at diagnosis in women with MRKH syndrome. MRKH syndrome may have a familial and hereditary dimension. Abstract Introduction Mayer‐Rokitansky‐Küster‐Hauser (MRKH) syndrome with utero‐vaginal aplasia is the most severe ...
Auriane Cospain+17 more
wiley +1 more source
Infinitesimal Perturbation Analysis for Personalized Cancer Therapy Design [PDF]
We use a Stochastic Hybrid Automaton (SHA) model of prostate cancer evolution under intermittent androgen suppression (IAS) to study a threshold-based policy for therapy design. IAS is currently one of the most widely used treatments for advanced prostate cancer.
arxiv
Ethical considerations for non‐procreative uterus transplantation
Abstract The growing demand for uterus transplantation (UTx) invites continued philosophical evaluation of the function of UTx (and what constitutes its ‘success’), as well as the recipient eligibility for UTx. Currently, UTx caters to partnered, cisgender women of childbearing age looking to get pregnant and give birth to a biogenetically related ...
J. Y. Lee
wiley +1 more source
Stability of a Peer-to-Peer Communication System [PDF]
This paper focuses on the stationary portion of file download in an unstructured peer-to-peer network, which typically follows for many hours after a flash crowd initiation. The model includes the case that peers can have some pieces at the time of arrival.
arxiv
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disease caused by the progressive deposition of extracellular amyloid beta (Aβ) and intracellular neurofibrillary tangles (NFTs). Of note, metabolic disorders such as insulin resistance (IR) and type 2 diabetes (T2D) are associated with the development of brain IR and associated neurodegeneration.
Mansour A. Alsaleem+9 more
wiley +1 more source
Abstract Polycystic ovary syndrome (PCOS), one of the most common endocrine disorders in reproductive‐aged women, is associated with metabolic disturbances. The present study aimed to examine changes in body weight (BW) and glucose and insulin tolerance in a prenatally‐androgenized (PNA) rat model of PCOS compared to control with increasing age ...
Mahbanoo Farhadi‐Azar+4 more
wiley +1 more source
Enhancing intersex healthcare: A qualitative study of parental perspectives on the role of genetics
Abstract Intersex individuals, encompassing people with diverse sex characteristics that do not fit binary frameworks of sex, have long faced a history of medical secrecy, discrimination, and societal stigma, contributing to their limited social visibility.
Kayla Horowitz+4 more
wiley +1 more source
Modeling Long-term Outcomes and Treatment Effects After Androgen Deprivation Therapy for Prostate Cancer [PDF]
Analyzing outcomes in long-term cancer survivor studies can be complex. The effects of predictors on the failure process may be difficult to assess over longer periods of time, as the commonly used assumption of proportionality of hazards holding over an extended period is often questionable.
arxiv