Results 11 to 20 of about 30,274 (252)

Complete androgen insensitivity syndrome with Sertoli cell tumour in a 27-year-old married woman: a case report

African Journal of Urology, 2023
Background Androgen insensitivity syndrome is a rare X-linked disorder of sex development that results from mutations in the androgen receptors leading to failure of normal masculinization of the external genitalia in genetically male individuals.
Mumini Wemimo Rasheed, Najeem Adedamola Idowu, Adebayo Ayoade Adekunle, Joseph Olusola Olarewaju, Latifat Tunrayo Oduola-owoo, Foluke Omolara Odetayo, Felix Abiodun Omolade, Akinremi Tosin Opeyemi   +7 more
doaj   +2 more sources

Complete androgen insensitivity syndrome in a 13-year-old Lebanese child, reared as female, with bilateral inguinal hernia: a case report

Journal of Medical Case Reports, 2021
Background Androgen insensitivity syndrome is a rare X-linked disorder of sex development, caused by mutations in the androgen receptor. In this case, a 13-year-old child, reared as female, presenting for primary amenorrhea, was diagnosed with complete ...
Stephanie Farah, Dana El Masri, Kamal Hirbli   +2 more
doaj   +2 more sources

Complete Androgen Insensitivity Syndrome: A Rare Case of Prenatal Diagnosis

Revista Brasileira de Ginecologia e Obstetrícia, 2021
With the widespread uptake of noninvasive prenatal testing (NIPT), a larger cohort of women has access to fetal chromosomal sex, which increases the potential to identify prenatal sex discordance. The prenatal diagnosis of androgen insensitivity syndrome
Maria Liz Coelho, Elisa Soares, Marília Freixo, Pedro Brandão, Carla Marinho, Juliana Rocha, Graça Rodrigues   +6 more
doaj   +2 more sources

Complete androgen insensitivity syndrome or testicular feminization: review of literature based on a case report

The Pan African Medical Journal, 2016
Testicular feminization, or the androgen insensitivity syndrome, is a rare disease. Because of various abnormalities of the X chromosome, a male, genetically XY, has some physical characteristics of a woman or a full female phenotype. Indeed the androgen
Regragui Souhail, Slaoui Amine, Abounouh Nadia, Karmouni Tarik, El Khader Khalid, Koutani Abdellatif, Ibn Attya Ahmed   +6 more
doaj   +2 more sources

Molecular mechanism of androgen receptor mutation in multigenerational mild androgen insensitivity syndrome. [PDF]

Endocr Connect
Objective: Androgen insensitivity syndrome (AIS) due to androgen receptor (AR) mutations creates a spectrum of clinical presentations based on residual AR function with the mildest impairment creating mild AIS (MAIS) whose undefined molecular mechanism ...
Pandher R, Chang R, Chang Y, Hibbs DE, Du JJ, McGrath K, Heather A, Jayadev V, Handelsman DJ.   +8 more
europepmc   +2 more sources

Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia [PDF]

Endocrinology and Metabolism, 2015
Gynecomastia is a benign enlargement of the male breast caused by the proliferation of glandular breast tissue. Determining the various causes of gynecomastia such as physiological causes, drugs, systemic diseases, and endocrine disorders is important ...
Sung Won Lee, Dong Shin Kwak, In Sub Jung, Joo Hee Kwak, Jung Hwan Park, Sang Mo Hong, Chang Bum Lee, Yong Soo Park, Dong Sun Kim, Woong Hwan Choi, You Hern Ahn   +10 more
doaj   +4 more sources

LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome. [PDF]

Sci Rep
Androgen insensitivity syndrome (AIS) is a difference of sex development (DSD) characterized by different degrees of undervirilization in individuals with a 46,XY karyotype despite normal to high gonadal testosterone production.
Pozojevic J, Sivaprasad R, Laß J, Haarich F, Trinh J, Kakar N, Schulz K, Händler K, Verrijn Stuart AA, Giltay JC, van Gassen KL, Caliebe A, Holterhus PM, Spielmann M, Hornig NC.   +14 more
europepmc   +2 more sources

Molecular genetics and general management of androgen insensitivity syndrome. [PDF]

Intractable Rare Dis Res, 2023
Androgen insensitivity syndrome (AIS) is a rare genetic disorder that affects the development of the male reproductive system in individuals with a 46,XY karyotype.
Chen Z, Li P, Lyu Y, Wang Y, Gao K, Wang J, Lan F, Chen F.   +7 more
europepmc   +2 more sources

Complete androgen insensitivity syndrome: a case report and literature review. [PDF]

J Int Med Res, 2023
Complete androgen insensitivity syndrome (CAIS) is a rare disease that can be easily misdiagnosed. Before puberty, this condition is easily misdiagnosed as an inguinal hernia.
Guo M, Huang JC, Li CF, Liu YY.
europepmc   +2 more sources

Complete androgen insensitivity syndrome: Dilemmas for further management after gonadectomy

Journal of Human Reproductive Sciences, 2019
Complete androgen insensitivity syndrome is a rare condition, wherein a genetic male is phenotypically female and is raised as a female. Treatement requires timely gonadectomy, need for long term hormonal replaceent therapy, psycological and genetic ...
Pratibha Singh, Meenakshi Gothwal, Garima Yadav, Kuldeep Singh   +3 more
doaj   +2 more sources