Androgen Insensitivity Syndrome [PDF]
Seminars in Reproductive Medicine, 2012 The androgen insensitivity syndromes (AIS) fall within the generic category of 46,XY DSD (disorder of sex development) and present as phenotypes associated with complete or partial resistance to the action of androgens. Three categories are recognized: complete androgen insensitivity syndrome (CAIS), partial androgen insensitivity syndrome (PAIS), mild
Trevor Bunch +3 more
+10 more sources
Clinical characteristics, AR gene variants, and functional domains in 64 patients with androgen insensitivity syndrome. [PDF]
J Endocrinol Invest, 2023 Background Androgen insensitivity syndrome (AIS) is caused by abnormal androgen receptor (AR) genes that show variable genotypes and phenotypes. However, the correlation between genotype and phenotype is unclear.
Liu Q, Yin X, Li P.
europepmc +2 more sources
Metabolic effects of estradiol versus testosterone in complete androgen insensitivity syndrome. [PDF]
Endocrine, 2022 To study differences in metabolic outcomes between testosterone and estradiol replacement in probands with complete androgen insensitivity syndrome (CAIS). In this multicentre, double-blind, randomized crossover trial, 26 women with CAIS were included of
Auer MK +11 more
europepmc +2 more sources
Complete Androgen Insensitivity Syndrome: From Bench to Bed. [PDF]
Int J Mol Sci, 2021 Complete androgen insensitivity syndrome (CAIS) is due to complete resistance to the action of androgens, determining a female phenotype in persons with a 46,XY karyotype and functioning testes.
Tyutyusheva N +6 more
europepmc +2 more sources
Evaluating complete androgen insensitivity syndrome with a multimodal sonography system. [PDF]
Quant Imaging Med Surg, 2022 to be testicles, which were smaller than normal testicles, were detected in the upper pelvic cavity; however, ovotestes could not be definitively excluded; (II) under the guidance of sonography, catheterization was performed smoothly, followed by ...
Xu Z, Peng C, Zhang L, Huang Q.
europepmc +2 more sources
COMPLETE ANDROGEN INSENSITIVITY SYNDROME [PDF]
International Journal of Advanced Research, 2016 D.G.O Dr.L.Santhanalakshmi
openalex +3 more sources
Androgen insensitivity syndrome [PDF]
Current Opinion in Endocrinology, Diabetes & Obesity, 2014 Androgen insensitivity syndrome (AIS) can present with a wide range of phenotypes, and its management requires a multidisciplinary approach from diagnosis in infancy to adulthood. This review provides an update on some clinical and genetic aspects in AIS.
Rieko Tadokoro-Cuccaro, Ieuan A. Hughes
+6 more sources
Differences of adrenal-derived androgens in 5α-reductase deficiency versus androgen insensitivity syndrome. [PDF]
Clin Transl Sci, 2022 Steroid 5α‐reductase type 2 deficiency (5α‐RD2) and androgen insensitivity syndrome (AIS) are difficult to distinguish clinically and biochemically, and adrenal‐derived androgens have not been investigated in these conditions using modern methods.
Han B +9 more
europepmc +2 more sources
Mild Androgen Insensitivity Syndrome presenting in male with infertility and sexual difficulties
Bangladesh Journal of Medical Science, 2023 Androgen insensitivity syndrome has a wide spectrum of presentations. It results from a mutation in androgen receptor (AR) gene. It ranges from mild androgen insensitivity syndrome (MAIS) which is the mildest form to complete androgen insensitivity ...
A. Mukhtar +4 more
semanticscholar +1 more source
Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
British Journal of Clinical Pharmacology, EarlyView., 2023 Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius +2 more
wiley +1 more source