Results 61 to 70 of about 29,125 (205)

Understanding Exosomes in Hair Regeneration

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad   +3 more
wiley   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

Combination oral minoxidil and spironolactone for the treatment of androgenetic alopecia in adolescent females / supplemental files

open access: yes, 2020
supplemental files for JAAD article, Combination oral minoxidil and spironolactone for the treatment of androgenetic alopecia in adolescent ...
Craiglow, B (via Mendeley Data)   +1 more
core   +2 more sources

Androgen receptor accelerates premature senescence of human dermal papilla cells in association with DNA damage. [PDF]

open access: yesPLoS ONE, 2013
The dermal papilla, located in the hair follicle, expresses androgen receptor and plays an important role in hair growth. Androgen/Androgen receptor actions have been implicated in the pathogenesis of androgenetic alopecia, but the exact mechanism is not
Yi-Chien Yang   +5 more
doaj   +1 more source

Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu   +7 more
wiley   +1 more source

Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Graphical overview of targeted protein degradation: mechanisms, molecular determinants, delivery strategies, and therapeutic development. This graphical abstract summarizes the major degradation pathways involved in targeted protein degradation, including the ubiquitin–proteasome system, endocytosis–lysosome pathway, and autophagy‐dependent degradation.
Huaijuan Guo   +8 more
wiley   +1 more source

New trends in the treatment of androgenetic alopecia

open access: yes
Androgenetic alopecia is the most common form of non-cicatricial hair loss, affecting a significant proportion of the population, particularly men.
Michał Smoczok   +2 more
core   +1 more source

A Natural Inhibitor, 1′S-1′-Acetoxychavicol Acetate, Against Testosterone-Induced Alopecia via NADPH Oxidase Regulation

open access: yesMolecules
Androgenetic alopecia is associated with testosterone-mediated anagen-to-catagen transition and matrix keratinocyte apoptosis in hair follicle cells.
Kkotnara Park   +11 more
doaj   +1 more source

Exploring the lived experiences of LGBTQIA+ young people with visible differences: Being ‘double different’

open access: yesBritish Journal of Health Psychology, Volume 31, Issue 4, November 2026.
Abstract Objectives Existing research suggests young people with visible differences can experience a range of psychosocial challenges, such as low self‐esteem and increased anxiety and depression. However, young people from minoritised groups are not well represented in visible difference research.
Emma Waite   +3 more
wiley   +1 more source

Impact of male androgenetic alopecia on a Jordanian cohort measured using the Dermatology Life Quality Index

open access: yesJournal of International Medical Research
Objectives This study aimed to assess the impact of androgenetic alopecia on the quality of life of individuals in a Jordanian cohort using the Dermatology Life Quality Index and compare it with that in other communities.
Jihan Muhaidat   +6 more
doaj   +1 more source

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