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Andrographolide, A Natural Antioxidant: An Update [PDF]
Antioxidants, 2019 Traditionally, Andrographis paniculata has been used as an herbal remedy for lung infection treatments. Its leaves contain a diterpenoid labdane called andrographolide responsible for a wide range of biological activities such as antioxidant, anti-inflammatory, and anti-cancer properties.
Annabelle Cesaro +2 more
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An insight into the pharmacological and analytical potential of Andrographolide
Fundamental & Clinical Pharmacology, 2022AbstractAndrographis paniculata is an annual medicinal herb from the family Acanthaceae. Andrographolide is generally considered an essential bioactive component of plant A. paniculata. Since ancient times, it has been widely recognized for its therapeutic qualities and has attracted the scientific and medical communities' attention.
Pallavi Agrawal, Maya S. Nair
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Oxidation studies on Andrographolide
Natural Product Research, 2006Jones oxidation of Andrographolide (1), gave mixture of three products (3-dehydroandrographolide (5), 3,19-bis dehydroandrographolide (6) and 19-dehydroandrographolide (7). Tritylation of andrographolide at C19-OH resulted to products 8 and diene 9, which can be converted to its acetate 10 and oxidation product 11.
Vijayavitthal T, Mathad +2 more
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On the structure of andrographolide
Recueil des Travaux Chimiques des Pays-Bas, 1951AbstractThe infrared spectrum of andrographolide shows the presence of a five‐membered unsaturated lactone‐ring and a terminal methylene group in the molecule. On catalytic hydrogenation more than four atoms of hydrogen are taken up. A new diacetyl‐anhydro‐andrographolide is described.
R. J. C. Kleipool +1 more
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*Semisynthesis and cytotoxic activities of andrographolide analogues [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2006 Andrographolide 1, a diterpenoid lactone of the plant Andrographis paniculata, known to possess antitumour activity in in vitro and in vivo breast cancer models was subjected to semisynthesis leading to the preparation of a number of novel compounds.
Johnson Stanslas
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Helvetica Chimica Acta, 1951
AbstractDie vorliegende Arbeit befasst sich mit der Konstitutionsaufklärung des Andrographolids, eines Bitterstoffes der indischen Medizinalpflanze Andrographis paniculata Nees. Verschiedene, in der früheren Literatur vorkommende Widersprüche und Unstimmigkeiten konnten dabei abgeklärt werden.
R. Schwyzer, H. G. Biswas, P. Karrer
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AbstractDie vorliegende Arbeit befasst sich mit der Konstitutionsaufklärung des Andrographolids, eines Bitterstoffes der indischen Medizinalpflanze Andrographis paniculata Nees. Verschiedene, in der früheren Literatur vorkommende Widersprüche und Unstimmigkeiten konnten dabei abgeklärt werden.
R. Schwyzer, H. G. Biswas, P. Karrer
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Biosynthesis of andrographolide in Andrographis paniculata
Phytochemistry, 2010Andrographolide, a diterpene lactone, is isolated from Andrographis paniculata which is well known for its medicinal properties. The biosynthetic route to andrographolide was studied using [1-(13)C]acetate, [2-(13)C]acetate and [1,6-(13)C(2)]glucose. The peak enrichment of eight carbon atoms in the (13)C NMR spectra of andrographolide suggested that ...
Nishi, Srivastava, Anand, Akhila
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Chemical Transformation of Andrographolide.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Mahesh Pal +2 more
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