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Broad-spectrum antiviral properties of andrographolide

Archives of Virology, 2016
Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated from various plants of the genus Andrographis, commonly known as 'creat'. This purified compound has been tested for its anti-inflammatory effects in various stressful conditions, such as ischemia, pyrogenesis, arthritis, hepatic or neural toxicity, carcinoma,
Swati, Gupta, K P, Mishra, Lilly, Ganju
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HPLC determination of andrographolide in rat whole blood: study on the pharmacokinetics of andrographolide incorporated in liposomes and tablets

Biomedical Chromatography, 2007
AbstractA sensitive and simple high‐performance liquid chromatographic method with UV detection was developed and validated for the determination of andrographolide in rat whole blood. Carbamazepine was employed as internal standard and the blood sample was extracted with chloroform.
Xu-Bin, Suo, Han, Zhang, Yu-Qiang, Wang
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Andrographolide and its Analogs

Andrographolide is a pharmacologically significant labdane diterpenoid primarily isolated from <i>Andrographis paniculata</i>, and later, from many of its allied species. <i>A. paniculata</i> is used in many Indian traditional and alternative medicinal systems for treating several human ailments.
S. Karuppusamy, N. Janakiraman
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Esterification of andrographolide

Esterification reaction of andrographolide with acid anhydride and acid chloride, including acetic anhydride, butyric anhydride, benzoyl chloride, heptanoyl chloride and stearoyl chloride at various reaction conditions have been studied. The products of the reaction in all cases were mono- and di-acyl derivatives of dehydroandrographolide, but at room ...
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Andrographolide

Tetrahedron, 1965
M.P. Cava   +3 more
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The structure of andrographolide

Tetrahedron, 1962
M.P. Cava   +4 more
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Biological Activities of Andrographolide and Some Semi-synthesis Nonbitter Andrographolides

Planta Medica, 2011
C Aromdee   +6 more
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Andrographolide: the Active Principle of Kalmegh

Nelumbo
The paper gives a critical review of the chemistry of andrographolide, the active principle of Andrographis paniculata Nees, the common bitter popularly known as Kalmegh. It was isolated in 1911 and although the gross chemical nature as a trihydroxy diterpene lactone was known much earlier, it took more than fifty years for its complete elucidation.
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Andrographolide and its derivatives: Current achievements and future perspectives

European Journal of Medicinal Chemistry, 2021
Shufeng Li, Haiwei Xu
exaly  

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