Results 141 to 150 of about 46,058 (304)
ABSTRACT Background This study investigates the impact of hormone therapy (HT) on the diagnostic performance of 18F‐piflufolastat PET/CT in OSPREY (NCT02981368) cohort B patients with recurrent or metastatic prostate cancer. Methods 18F‐piflufolastat PET/CT was evaluated in OSPREY cohort B patients (n = 117 men) with elevated prostate‐specific antigen (
Lawrence Saperstein+9 more
wiley +1 more source
ABSTRACT Objective Prostate‐specific antigen (PSA)‐based screening has reduced prostate cancer (PCa) mortality but is associated with overdiagnosis/overtreatment. We developed and evaluated a blood‐based S2,3PSA% test to address the limitations of PSA‐based screening for PCa.
Hikari Miura+17 more
wiley +1 more source
ABSTRACT Background Approximately 50% of prostate cancer (PCa) patients meet the National Comprehensive Cancer Network (NCCN) guidelines for germline testing at diagnosis. However, the selection of genes for testing, their supporting evidence, and clinical interpretation remain poorly understood.
Jianfeng Xu+19 more
wiley +1 more source
Sexual Abstinence and Immobilisation Stress Decreased Nitrate + Nitrite Concentration and Increased Necrotic of Penile Corpus Cavernosum Smooth Muscle and Endothelial Cells of Adult Male Mice [PDF]
Sexual intercourse in adult people is not only related to reproduction,recreation and better relation but also for maintaining good health. Regular andfrequent sexual intercourse has protective role for cardiovascular disease, Malignancyand often related
Karmaya, I. N. (I)+2 more
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A Multimarker Model for Prostate Cancer Risk Assessment: Improving Diagnostic Accuracy Beyond PSA
ABSTRACT Objective This study aimed to evaluate the association between biochemical markers and prostate cancer (PCa) risk by analyzing patients with benign prostatic hyperplasia (BPH) and PCa. Additionally, the study sought to assess the diagnostic accuracy of a multimarker model compared to prostate‐specific antigen (PSA) alone.
Penglu Yang, Bin Yang
wiley +1 more source
ABSTRACT Background An accurate estimation of progression risk in patients with prostate cancer (PCa) amenable to active surveillance (AS) is still an unmet need. Among available biomarkers, we considered Prolaris cell‐cycle progression (CCP) test, “triple hit” phenotype (ERG overexpression, PTEN and prostein expression loss) and elevated expression ...
Marco Oderda+14 more
wiley +1 more source
Sperm morphology: Evaluating its clinical relevance in contemporary fertility practice
Background The World Health Organization (WHO) recommends reporting sperm morphology in a standard semen analysis. However, the clinical utility and prognostic value of morphology is often debated. Methods We reviewed and summarized studies that assessed
Daniel L. Pelzman, Jay I. Sandlow
doaj +1 more source
Abstract Prostate cancer (PCa) is a multifaceted disease that envelops 1.41 million new cases globally. It is the second most common cancer reported in men. Its heterogeneity and indolent growth, coupled with incompetent early screening methods such as serum prostate‐specific antigen level estimations and digital rectal examinations, contribute to its ...
Anveshika Manoj+2 more
wiley +1 more source
In-vitro application of pentoxifylline preserved ultrastructure of spermatozoa after vitrification in asthenozoospermic patients [PDF]
PURPOSE: To evaluate the effect of in vitro application of pentoxifylline (PX) on sperm parameters and ultrastructure after vitrification in asthenozoospermic patients. MATERIALS AND METHODS: A total of 30 asthenozoospermic semen samples (aged 25-45
Khalili, Ma+7 more
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