Results 181 to 190 of about 50,976 (393)
A non‐hormonal reversible contraceptive targeting GSK3α, a protein kinase, essential for epididymal sperm maturation
Andrology, EarlyView.Abstract Background and objectives
Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.Mustfa Kabi, Aditi Khamamkar, Kwaku Kyei‐Baffour, Michel Weïwer, Srinivasan Vijayaraghavan, Souvik Dey +5 morewiley +1 more sourceThe current treatment of erectile dysfunction [PDF]
, 2016 Erectile dysfunction (ED) is the inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse. It is the most frequent sexual dysfunction in elderly men and its prevalence increases with age.Benea, Vasile, Georgescu, Simona R., Mitran, Cristina I., Mitran, Mădălina I., Sarbu, Maria Isabela, Tampa, Mircea +5 morecore +2 more sourcesAndrology [PDF]
Human Reproduction, 2012 Hu, J C Y, Seo, B K, Neri, Q V, Rozenwaks, Z, Palermo, G D, Fields, T, Neri, Q V, Monahan, D, Rosenwaks, Z, Palermo, G D, Szkodziak, P, Plewka, K, Wozniak, S, Czuczwar, P, Mroczkowski, A, Leon, C Lorenzo, Hernandez, J, Mendez, E Chinea, Lorenzo, C Concepcion, Perez, V Sanabria, Puopolo, M, Palumbo, A, Toth, B, Franz, C, Montag, M, Boing, A, Strowitzki, T, Nieuwland, R, Griesinger, G, Schultze-Mosgau, A, Cordes, T, Depenbusch, M, Diedrich, K, Vloeberghs, V, Verheyen, G, Camus, M, de Velde, H Van, Goossens, A, Tournaye, H, Coppola, G, Caprio, G Di, Wilding, M, Ferraro, P, Esposito, G, Matteo, L Di, Dale, R, Coppola, G, Dale, B, Daoud, S, Auger, J, Wolf, J P, Dulioust, E, Lafuente, R, Lopez, G, Brassesco, M, Hamad, M, Montenarh, M, Hammadeh, M, Robles, F, Magli, M C, Crippa, A, Pescatori, E, Ferraretti, A P, Gianaroli, L, Zahiri, M, Movahedin, M, Mowla, S J, Noruzinia, M, Crippa, A, Ferraretti, A P, Magli, M C, Crivello, A M, Robles, F, Gianaroli, L, Sermondade, N, Dupont, C, Hafhouf, E, Cedrin-Durnerin, I, Poncelet, C, Benzacken, B, Levy, R, Sifer, C, Ferfouri, F, Boitrelle, F, Clement, P, Gomes, D Molina, Bailly, M, Selva, J, Vialard, F, Yaprak, E, Basar, M, Guzel, E, Arda, O, Irez, T, Norambuena, P, Krenkova, P, Tuettelmann, F, Kliesch, S, Paulasova, P, Stambergova, A, Macek, M, Macek, M, Rivera, R, Garrido-Gomez, T, Galletero, S, Meseguer, M, Dominguez, F, Garrido, N, Mallidis, C, Sanchez, V, Weigeng, L, Redmann, K, Wistuba, J, Gross, P, Wuebbelling, F, Fallnich, C, Burger, M, Kliesch, S, Schlatt, S, Carchenilla, M San Celestino, Castro, A Pacheco, Sanjurjo, P Simon, Ballesteros, A Molinero, Garcia, S Rubio, Velasco, J A Garcia, Macanovic, B, Otasevic, V, Korac, A, Vucetic, M, Garalejic, E, Burmazovic, I Ivanovic, Filipovic, M R, Buzadzic, B, Stancic, A, Jankovic, A, Velickovic, K, Golic, I, Markelic, M, Korac, B, Gosalvez, J, Ruiz-Jorro, M, Garcia-Ochoa, C, Sachez-Martin, P, Martinez-Moya, M, Caballero, P, Hasegawa, N, Fukunaga, N, Nagai, R, Kitasaka, H, Yoshimura, T, Tamura, F, Kato, M, Nakayama, K, Oono, H, Kojima, E, Yasue, K, Watanabe, H, Asano, E, Hashiba, Y, Asada, Y, Das, M, Al-Hathal, N, San-Gabriel, M, Phillips, S, Kadoch, I J, Bissonnette, F, Holzer, H, Zini, A, Zebitay, A G, Irez, T, Ocal, P, Sahmay, S, Karahuseyinoglu, S, Usta, T, Repping, S, Silber, S, Wely, M Van, Datta, A, Nayini, K, Eapen, A, Barlow, S, Lockwood, G, Tavares, R, Baptista, M, Publicover, S J, Ramalho-Santos, J, Vaamonde, D, Rodriguez, I, Diaz, A, Darr, C, Chow, V, Ma, S, Smith, R, Jeria, F, Rivera, J, Gabler, F, Nicolai, H, Cunha, M, Viana, P, Goncalves, A, Pacey, Allan, Fujii, Y +201 moreopenaire +4 more sourcesKisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Andrology, EarlyView.Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara +5 morewiley +1 more sourceLuteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, EarlyView.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...Ilpo T. Huhtaniemiwiley +1 more sourceComprehensive diagnostic and therapeutic approach to male factor infertility aimed at natural fertility: A multicentric retrospective cohort study
Andrology, EarlyView.Abstract Background
In infertile couples whose male partner has alterations in semen parameters frequently, a comprehensive andrological approach is lacking and approximately 30–50% are classified as idiopathic infertility. These couples are often directly addressed to assisted reproduction techniques (ARTs).Giuseppe Grande, Andrea Garolla, Andrea Graziani, Anna Laura Astorri, Maria Vittoria Cammarota, Annamaria Merola, Maria Pia Polidori, Emanuela Lulli, Enrico Busato, Francesco Pesce, Giuseppina Pompa, Alfredo Pontecorvi, Domenico Milardi, Alberto Ferlin +13 morewiley +1 more source