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Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors are estimated to contribute to 30–50% of cases of infertility. Infertility or reduced fertility can result from testicular dysfunction, endocrinopathies,
Michael L Eisenberg +2 more
exaly +6 more sources
It is estimated that infertility affects 8–12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples.
Ashok Agarwal +2 more
exaly +5 more sources
Genetic aspects of male infertility
Currently, infertility affects up to 140 million people worldwide. It is considered that the male factor is responsible for nearly a half of problems in obtaining pregnancy.
Bartosz Witczak +2 more
doaj +2 more sources
Endocrinopathies and Male Infertility
Male infertility is approaching a concerning prevalence worldwide, and inflicts various impacts on the affected couple. The hormonal assessment is a vital component of male fertility evaluation as endocrine disorders are markedly reversible causatives of
Pallav Sengupta +3 more
doaj +2 more sources
Excessive amounts of reactive oxygen species (ROS) cause a state of oxidative stress, which result in sperm membrane lipid peroxidation, DNA damage and apoptosis, leading to decreased sperm viability and motility. Elevated levels of ROS are a major cause
Damayanthi Durairajanayagam +3 more
doaj +3 more sources
A novel loss-of-function mutation in MCMDC2 is associated with male infertility [PDF]
Ori Cohen +6 more
doaj +2 more sources
According to the World Health Organization (WHO), infertility is the failure of a couple to achieve pregnancy after one year of consistent unprotected sex. Male factors contribute to about 50 percent of all infertility cases. Male infertility is a multifactorial disease that can stem from multiple etiologies which can be congenital or acquired.
Dhikhirullahi O, Zhang Z.
europepmc +4 more sources
The application of MACS non-apoptotic sperm selection in infertility clinics is controversial since the published literature does not agree on its effect on reproductive outcomes. Therefore, it is not part of the routine clinical practice.
María Gil Juliá +8 more
doaj +1 more source
Introduction: Microdissection Testicular Sperm Extraction (micro-TESE) is a surgical method used for retrieving sperm from men with non-obstructive azoospermia.
Khalid Alrabeeah +4 more
doaj +1 more source
“Immunobiology of male infertility”.
Experimental and clinical data reported in the literature emphasize the important role that immune factors may play in the genesis of male infertility even if many problems still remain to be solved.
ISIDORI, Aldo +2 more
core +4 more sources

