Results 1 to 10 of about 87,451 (299)

Single-Cell Insights Into Pathogenic Profile of Orchitis and SREBP2-Associated Cholesterol Dysregulation in Spermatogenic Failure. [PDF]

Adv Sci (Weinh)
A first single‐cell atlas of human orchitis reveals coordinated germ‐cell loss, somatic niche dysfunction, and immune‐metabolic remodeling. Aberrant SREBP2 activation in testicular somatic cells emerges as a central pathogenic node, while Fatostatin‐mediated inhibition of the SREBP pathway improves spermatogenesis, fibrosis, and lipid accumulation in a
Tang Y, Jiang Q, Liu Y, Zhang W, Cui L, Lu X, Zhuang Z, Cheng J, Gao S, Fang Y, Hong K, Qiao J, Wang X, Jiang H, Zhang Z, Guo J, Liu Q.   +16 more
europepmc   +2 more sources

Correction: Research progress on the multidimensional mechanisms underlying impaired spermatogenesis induced by pathological microenvironment remodeling in chronic prostatitis. [PDF]

Front Immunol
Li J, Jiang Z, Luo W, Tang K, Liang D, Luo X, Liu L, Long Z, Huang H, Chen W, Zhang Y.   +10 more
europepmc   +1 more source

Loss of α-catenin in germ cells impairs spermatogenesis and flagellar function associated with teratozoospermia. [PDF]

Zool Res
Ha X, Li SJ, Zhao RL, Yang LY, He YQ, Peng L, Lv LT, Zhu XJ, Yang M, Yang ZL.   +9 more
europepmc   +1 more source

B3GALT4-dependent gangliosides are required for normal late spermatogenesis and male fertility. [PDF]

J Reprod Dev
Nagata S, Nishioka S, Ikawa M, Ozawa M.
europepmc   +1 more source

Potassium Dichromate Exposure and Sperm Quality in Rats: A Multi-Generational Study. [PDF]

Toxics
Savici J, Marc S, Boldura OM, Shalaby S, Oprescu M, Brezovan D, Muselin F, Igna V.   +7 more
europepmc   +1 more source

Emerging peptide and neuroendocrine strategies for TRT-induced reproductive suppression and functional male hypogonadism: a narrative review. [PDF]

Front Reprod Health
Cretu AM, Kamar AAM, Ciobica A, Puia D, Doroftei M, Doroftei B.   +5 more
europepmc   +1 more source

Sertoli cell oxidative stress as a convergent hazard endpoint for environmental toxicants: A systematic review, meta-analysis, and AOP-based assessment. [PDF]

Redox Biol
Wang K.
europepmc   +1 more source