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Testicular endothelial cells have been found to play an important role in spermatogenesis and fertility, but their mechanism is obscure. Exosomes released by various cells are recognized as cell–cell communication mediators during the initiation and ...
Wen-Peng Song +7 more
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Direct action through the Sertoli cells is essential for androgen stimulation of spermatogenesis [PDF]
Androgens act to stimulate spermatogenesis through androgen receptors (AR) on the Sertoli cells and peritubular myoid cells (PTM). Specific ablation of the AR in either cell type will cause a severe disruption of spermatogenesis.
Abel, M.H. +4 more
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Models of in vitro spermatogenesis
S.32-43Understanding the mechanisms that lead to the differentiation of male germ cells from their spermatogonial stem cells through meiosis to give rise to mature haploid spermatozoa has been a major quest for many decades.
Anand-Ivell, R. +3 more
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Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +1 more source
Background Spermatogenesis is an intricate process regulated by a finely organized network. The orange-spotted grouper (Epinephelus coioides) is a protogynous hermaphroditic fish, but the regulatory mechanism of its spermatogenesis is not well-understood.
Xi Wu +6 more
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Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
Baker, P.J. +8 more
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X chromosome inactivation during Drosophila spermatogenesis [PDF]
Genes with male- and testis-enriched expression are under-represented on the Drosophila melanogaster X chromosome. There is also an excess of retrotransposed genes, many of which are expressed in testis, that have “escaped” the X chromosome and moved to ...
Baines, J. +11 more
core +1 more source
Latar belakang: Metanol memiliki efek toksik melalui metabolitnya yaitu asam format yang mengakibatkan gangguan spermatogenesis. Ranitidine mempunyai enzim yang dapat menghambat terbentuknya metabolit asam format sehingga diharapkan akan mengurangi efek ...
James Otniel +2 more
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Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis. [PDF]
Tumor suppressor of lung cancer 1 (TSLC1), also known as SgIGSF, IGSF4, and SynCAM, is strongly expressed in spermatogenic cells undergoing the early and late phases of spermatogenesis (spermatogonia to zygotene spermatocytes and elongating spermatids to
Arends, Mark J. +9 more
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Spermatogenesis without spermiogenesis in Laudakia caucasia (Reptilia: Agamidae): the role of hibernation [PDF]
During hibernation period from Mid October to Late March, we removed testis of Laudakia caucasia. Based on histological and statistical analyses we obtained two phases in spermatogenesis in this lizard as follows: (a) from October to December, in which ...
N. Rastegar-Pouyani, F. Torki
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