Results 41 to 50 of about 121,335 (279)

Antipsychotics and spermatogenesis, which is the impact?: A review of literature

open access: yesEuropean Psychiatry, 2023
Introduction Antipsychotics are among the most widely prescribed molecules in psychiatry. Their sexual side effects are frequent, generally underestimated by clinicians and subjectively poorly tolerated by patients.
H. Belhadga, Z. Elmaataoui, H. Kisra
doaj   +1 more source

Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]

open access: yes, 2009
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H.   +4 more
core   +1 more source

The Prmt5-Vasa module is essential for spermatogenesis in Bombyx mori.

open access: yesPLoS Genetics, 2023
In lepidopteran insects, dichotomous spermatogenesis produces eupyrene spermatozoa, which are nucleated, and apyrene spermatozoa, which are anucleated.
Xu Yang   +12 more
doaj   +1 more source

Testicular degeneration and infertility following arbovirus infection [PDF]

open access: yes, 2018
Arboviruses can cause a variety of clinical signs including febrile illness, arthritis, encephalitis and hemorrhagic fever. The recent Zika epidemic highlighted the possibility that arboviruses may also negatively affect the male reproductive tract.
Dattena, Maria   +11 more
core   +1 more source

Novel Gene Regulation in Normal and Abnormal Spermatogenesis

open access: yesCells, 2021
Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic and epigenetic factors. With the development of new technologies (e.g., single-cell RNA sequencing), increasingly more regulatory genes related to spermatogenesis ...
Li Du   +7 more
doaj   +1 more source

Action of the Metalloproteinases in Gonadal Remodeling during Sex Reversal in the Sequential Hermaphroditism of the Teleostei Fish Synbranchus marmoratus (Synbranchiformes: Synbranchidae) [PDF]

open access: yes, 2018
Teleostei present great plasticity regarding sex change. During sex reversal, the whole gonadincluding the germinal epithelium undergoes significant changes, remodeling, and neoformation.However, there is no information on the changes that occur within ...
Antoneli, Fernanda   +3 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone   +4 more
wiley   +1 more source

Understanding spermatogenesis is a prerequisite for treatment

open access: yesReproductive Biology and Endocrinology, 2003
Throughout spermatogenesis multiplication, maturation and differentiation of germ cells results in the formation of the male gamete. The understanding of spermatogenesis needs detailed informations about the organization of the germinal epithelium, the ...
Schulze Wolfgang   +2 more
doaj   +1 more source

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

open access: yesiScience, 2021
Summary: Maintaining proteostasis is important for animal development. How proteostasis influences spermatogenesis that generates male gametes, spermatozoa, is not clear.
Qianxing Zou   +5 more
doaj   +1 more source

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