Antipsychotics and spermatogenesis, which is the impact?: A review of literature
Introduction Antipsychotics are among the most widely prescribed molecules in psychiatry. Their sexual side effects are frequent, generally underestimated by clinicians and subjectively poorly tolerated by patients.
H. Belhadga, Z. Elmaataoui, H. Kisra
doaj +1 more source
Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H. +4 more
core +1 more source
The Prmt5-Vasa module is essential for spermatogenesis in Bombyx mori.
In lepidopteran insects, dichotomous spermatogenesis produces eupyrene spermatozoa, which are nucleated, and apyrene spermatozoa, which are anucleated.
Xu Yang +12 more
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Testicular degeneration and infertility following arbovirus infection [PDF]
Arboviruses can cause a variety of clinical signs including febrile illness, arthritis, encephalitis and hemorrhagic fever. The recent Zika epidemic highlighted the possibility that arboviruses may also negatively affect the male reproductive tract.
Dattena, Maria +11 more
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Novel Gene Regulation in Normal and Abnormal Spermatogenesis
Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic and epigenetic factors. With the development of new technologies (e.g., single-cell RNA sequencing), increasingly more regulatory genes related to spermatogenesis ...
Li Du +7 more
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Action of the Metalloproteinases in Gonadal Remodeling during Sex Reversal in the Sequential Hermaphroditism of the Teleostei Fish Synbranchus marmoratus (Synbranchiformes: Synbranchidae) [PDF]
Teleostei present great plasticity regarding sex change. During sex reversal, the whole gonadincluding the germinal epithelium undergoes significant changes, remodeling, and neoformation.However, there is no information on the changes that occur within ...
Antoneli, Fernanda +3 more
core +2 more sources
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone +4 more
wiley +1 more source
Understanding spermatogenesis is a prerequisite for treatment
Throughout spermatogenesis multiplication, maturation and differentiation of germ cells results in the formation of the male gamete. The understanding of spermatogenesis needs detailed informations about the organization of the germinal epithelium, the ...
Schulze Wolfgang +2 more
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Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis
Summary: Maintaining proteostasis is important for animal development. How proteostasis influences spermatogenesis that generates male gametes, spermatozoa, is not clear.
Qianxing Zou +5 more
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